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A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia.免疫性血小板减少症中糖蛋白特异性直接血小板自身抗体检测的现代重新评估
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3
Long-term safety and efficacy of rituximab in 248 adults with immune thrombocytopenia: Results at 5 years from the French prospective registry ITP-ritux.利妥昔单抗治疗 248 例成人免疫性血小板减少症的长期安全性和有效性:来自法国前瞻性登记研究 ITP-ritux 的 5 年结果。
Am J Hematol. 2019 Dec;94(12):1314-1324. doi: 10.1002/ajh.25632. Epub 2019 Oct 8.
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Use of Romiplostim during pregnancy as a rescue therapy in primary immune thrombocytopenia: Literature review and case description.妊娠期间使用罗米司亭作为原发性免疫性血小板减少症的抢救治疗:文献复习和病例描述。
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Autologous Indium-oxinate-labelled platelet sequestration study in patients with immune thrombocytopenia treated by thrombopoietin receptor-agonists.血小板生成素受体激动剂治疗的免疫性血小板减少症患者的自体氧肟酸铟标记血小板潴留研究
Br J Haematol. 2019 Aug;186(3):e44-e47. doi: 10.1111/bjh.15890. Epub 2019 Apr 4.
6
Romiplostim in adult patients with newly diagnosed or persistent immune thrombocytopenia (ITP) for up to 1 year and in those with chronic ITP for more than 1 year: a subgroup analysis of integrated data from completed romiplostim studies.罗米司亭治疗成人新诊断或持续性免疫性血小板减少症(ITP)长达 1 年,以及慢性 ITP 超过 1 年的患者:来自完成的罗米司亭研究综合数据的亚组分析。
Br J Haematol. 2019 May;185(3):503-513. doi: 10.1111/bjh.15803. Epub 2019 Feb 21.
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Long-term fostamatinib treatment of adults with immune thrombocytopenia during the phase 3 clinical trial program.在 3 期临床试验项目中,接受 fostamatinib 长期治疗的成人免疫性血小板减少症。
Am J Hematol. 2019 May;94(5):546-553. doi: 10.1002/ajh.25444. Epub 2019 Mar 13.
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Health-related quality of life in children with chronic immune thrombocytopenia treated with eltrombopag in the PETIT study.在 PETIT 研究中,接受艾曲波帕治疗的慢性免疫性血小板减少症儿童的健康相关生活质量。
Br J Haematol. 2019 Apr;185(1):102-106. doi: 10.1111/bjh.15732. Epub 2018 Dec 27.
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Immune thrombocytopenia: improving quality of life and patient outcomes.免疫性血小板减少症:改善生活质量和患者预后。
Patient Relat Outcome Meas. 2018 Nov 27;9:369-384. doi: 10.2147/PROM.S140932. eCollection 2018.
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Platelet transfusion practices in immune thrombocytopenia related hospitalizations.免疫性血小板减少症相关住院患者的血小板输注实践
Transfusion. 2019 Jan;59(1):169-176. doi: 10.1111/trf.15069. Epub 2018 Dec 5.

更新的原发性免疫性血小板减少症的调查和管理国际共识报告。

Updated international consensus report on the investigation and management of primary immune thrombocytopenia.

机构信息

Academic Haematology Unit, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

McMaster Centre for Transfusion Research, Department of Medicine and Department of Pathology and Molecular Medicine, McMaster University and Canadian Blood Services, Hamilton, ON, Canada.

出版信息

Blood Adv. 2019 Nov 26;3(22):3780-3817. doi: 10.1182/bloodadvances.2019000812.

DOI:10.1182/bloodadvances.2019000812
PMID:31770441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6880896/
Abstract

Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia (ITP). This article is an update of the International Consensus Report published in 2010. A critical review was performed to identify all relevant articles published between 2009 and 2018. An expert panel screened, reviewed, and graded the studies and formulated the updated consensus recommendations based on the new data. The final document provides consensus recommendations on the diagnosis and management of ITP in adults, during pregnancy, and in children, as well as quality-of-life considerations.

摘要

在过去的十年中,免疫性血小板减少症(ITP)患者的治疗实践发生了许多变化和发展。本文是 2010 年发表的国际共识报告的更新版。我们进行了批判性的审查,以确定 2009 年至 2018 年期间发表的所有相关文章。一个专家小组筛选、审查和评估了这些研究,并根据新数据制定了更新的共识建议。最终文件就成人、妊娠期和儿童 ITP 的诊断和管理以及生活质量问题提供了共识建议。