Cherry D A
Department of Anesthesia & Intensive Care, Flinders Medical Centre, Australia.
Acta Anaesthesiol Scand Suppl. 1987;85:54-9. doi: 10.1111/j.1399-6576.1987.tb02670.x.
From a practical and cost-effective viewpoint, the bolus administration of opiates via an implanted epidural catheter and portal injection system offers improved pain control for a good percentage of patients suffering pain secondary to cancer who are not responding to oral analgesia. However, considerable research is required into the mechanism of action, drug of choice, and optimal drug delivery system for the epidural administration of opiate drugs. Although this system is still in its infancy, it would be fair to say that it is one of the most significant advances for the control of pain in patients with cancer this century.
从实际和成本效益的角度来看，通过植入式硬膜外导管和门静脉注射系统推注阿片类药物，可为相当一部分对口服镇痛无反应的癌症继发疼痛患者提供更好的疼痛控制。然而，对于硬膜外给予阿片类药物的作用机制、首选药物和最佳给药系统，仍需要进行大量研究。尽管该系统仍处于起步阶段，但可以说它是本世纪癌症患者疼痛控制方面最重要的进展之一。
