Nikkanen V, Katainen P, Piiroinen O
Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.
Ann Chir Gynaecol Suppl. 1987;202:42-4.
To study the effect of progesterone support of the luteal phase in a stimulated cycle a subgroup of our IVF patients was treated with progesterone vaginal suppositoria. The treatment was initiated on the aspiration day. There was no significant difference in the pregnancy or abortion rate between the control group and the gestagen therapy group. However, it seems that progesterone support may increase the pregnancy rate but also the rate of spontaneous abortion. This suggests that the effective and early started progesterone supplementation of the luteal phase may cause the implantation of abnormal nonviable embryos.
为研究在促排卵周期中黄体期补充孕激素的效果，我们对一组体外受精（IVF）患者采用阴道用黄体酮栓剂进行治疗。治疗于取卵日开始。对照组和孕激素治疗组之间的妊娠率或流产率无显著差异。然而，似乎孕激素支持可能会提高妊娠率，但也会增加自然流产率。这表明有效的早期黄体期孕激素补充可能会导致异常无活力胚胎着床。
