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南非夸祖鲁-纳塔尔省四个 eThekwini 诊所中影响快速抗逆转录病毒治疗启动的因素。

Factors Influencing Rapid Antiretroviral Therapy Initiation at Four eThekwini Clinics, KwaZulu-Natal, South Africa.

机构信息

School of Nursing and Public Health, Discipline of Public Health Medicine, University of KwaZulu-Natal, Mazisi Kunene Road, Glenwood, Durban, 4041, South Africa.

School of Science, University of Namibia, Katima Mulilo Campus, Box 1096, Ngweze, Katima Mulilo, Namibia.

出版信息

AIDS Behav. 2022 Jun;26(6):1821-1828. doi: 10.1007/s10461-021-03530-3. Epub 2021 Nov 15.

DOI:10.1007/s10461-021-03530-3
PMID:34779941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9046140/
Abstract

Timely uptake of Antiretroviral therapy considerably improves the health of people living with the Human Immunodeficiency virus. We conducted a cross-sectional study of newly HIV diagnosed individuals in four clinics in eThekwini municipality, KwaZulu-Natal. Data was collected between June 2020 and December 2020. Participants completed an interviewer-administered questionnaire after HIV testing, on the day of HIV diagnosis. We evaluated factors influencing uptake of same-day ART initiation in eThekwini clinics, KwaZulu Natal, South Africa. Demographic information, health status, sexual behaviour, knowledge of universal test and treat (UTT), ART initiation uptake, and disclosure data was collected. Among the 403 participants, same-day initiation (SDI) was 69.2% (n = 279). We observed the number of sexual partners (aOR 0.35; 95% CI 0.15-0.81), HIV status of the partner (aOR 5.03; 95% CI 2.74-9.26) and knowledge of UTT (aOR 1.97; 95% CI 1.34-2.90) were identified as major factors influencing uptake of same-day ART initiation. More strategies are needed to achieve the SDI uptake within the framework of UTT.

摘要

及时接受抗逆转录病毒疗法可显著改善艾滋病毒感染者的健康状况。我们对夸祖鲁-纳塔尔省埃滕哈赫市的四个诊所新诊断出的艾滋病毒感染者进行了一项横断面研究。数据收集于 2020 年 6 月至 2020 年 12 月期间。参与者在艾滋病毒检测后、艾滋病毒诊断当天完成了由调查员管理的问卷。我们评估了在南非夸祖鲁-纳塔尔省埃滕哈赫诊所影响当天开始抗逆转录病毒治疗的因素。收集了人口统计学信息、健康状况、性行为、普遍检测和治疗(UTT)知识、抗逆转录病毒治疗起始率和披露数据。在 403 名参与者中,当天开始治疗(SDI)的比例为 69.2%(n=279)。我们观察到性伴侣数量(优势比 0.35;95%置信区间 0.15-0.81)、伴侣的艾滋病毒状况(优势比 5.03;95%置信区间 2.74-9.26)和 UTT 知识(优势比 1.97;95%置信区间 1.34-2.90)是影响当天开始抗逆转录病毒治疗的主要因素。需要采取更多策略,在 UTT 框架内实现 SDI 接受率。

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