Department of Endocrinology, Saint-Joseph University, Faculty of Medicine, Beirut, Lebanon.
Department of Biostatistics and Clinical Research Center, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
J Endocrinol Invest. 2022 Apr;45(4):763-772. doi: 10.1007/s40618-021-01701-6. Epub 2021 Nov 15.
Several studies have shown that COVID-19 pandemic has a negative impact on type 2 diabetic mellitus (T2DM) patients' quality of life (QoL). However, very few studies were performed in Middle Eastern countries.
The aim of the current study was to assess, the QoL and diabetes-specific QoL, treatment satisfaction and psychological distress of Lebanese patients with T2DMs using: the Audit of Diabetes-Dependent Quality of Life (ADDQoL), Diabetes Treatment Satisfaction Questionnaire status version (DTSQs) and Kessler 10 (K10) questionnaires and to compare results to those obtained during the pre-COVID-19 period.
461 patients with T2DM participated in the study; 52.6% men, 47.4% women; median age 59 years old. The respective median ADDQoL and DTSQs scores were - 2.2 (interval interquartile range (IQR) - 3.9, - 0.8) (range from - 9 maximum negative impact to + 3 maximum positive impact) and 30(IQR22-36) (range from 0 maximum dissatisfaction to 36 maximum satisfaction). K10 median score was 26(IQR18-35) (range from minimum score of 10 indicating no distress to maximum score of 50 indicating severe distress). Rural dwelling, lack of exercise, current smoking, diabetic complications, injectable diabetes treatment, and previous COVID-19 infection were all associated with significantly worse ADDQoL, DTSQs, and K10 score indicating greater distress. A significant worsening of ADDQoL scores followed onset of the pandemic with no significant change in DTSQs scores.
During the COVID-19 pandemic, T2DM Lebanese patients experienced more negative impact of diabetes on QoL and mental health. Those infected with COVID-19 also reported worse QoL, treatment satisfaction and mental health. This highlights the need for community and individual support.
多项研究表明,COVID-19 大流行对 2 型糖尿病(T2DM)患者的生活质量(QoL)产生负面影响。然而,在中东国家进行的研究很少。
本研究旨在使用糖尿病依赖生活质量评估量表(ADDQoL)、糖尿病治疗满意度问卷状态版(DTSQs)和 Kessler 10 问卷(K10)评估黎巴嫩 T2DM 患者的 QoL 和糖尿病特异性 QoL、治疗满意度和心理困扰,并将结果与 COVID-19 前时期的结果进行比较。
461 名 T2DM 患者参与了研究;男性占 52.6%,女性占 47.4%;中位年龄 59 岁。相应的 ADDQoL 和 DTSQs 中位数评分分别为-2.2(四分位距(IQR)-3.9,-0.8)(范围从最大负向影响-9 到最大正向影响+3)和 30(IQR22-36)(范围从最大不满意 0 到最大满意 36)。K10 的中位数评分为 26(IQR18-35)(范围从最小分数 10 表示无压力到最大分数 50 表示严重压力)。农村居住、缺乏运动、当前吸烟、糖尿病并发症、注射用糖尿病治疗和以前的 COVID-19 感染均与 ADDQoL、DTSQs 和 K10 评分显著恶化相关,表明压力更大。大流行开始后,ADDQoL 评分显著恶化,而 DTSQs 评分没有显著变化。
在 COVID-19 大流行期间,黎巴嫩 T2DM 患者经历了更多的糖尿病对 QoL 和心理健康的负面影响。感染 COVID-19 的患者也报告了更差的 QoL、治疗满意度和心理健康。这凸显了社区和个人支持的必要性。