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带真空密封引流的覆膜支架治疗静脉吸毒者感染性股动脉假性动脉瘤的疗效

Outcomes of Covered Stents With Vacuum Sealing Drainage For Treatment of Infected Femoral Pseudoaneurysms in Intravenous Drug Addicts.

作者信息

Zhang Mingyi, Zhang Haolong, Tang Bo, Fu Jian, Yan Haiyan, Luo Hailong

机构信息

Department of Vascular Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Department of Vascular Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Ann Vasc Surg. 2022 Apr;81:300-307. doi: 10.1016/j.avsg.2021.09.029. Epub 2021 Nov 12.

Abstract

OBJECTIVE

For treatment of infected femoral artery pseudoaneurysms (IFAPs) with the covered stent, debridement technique is important but frequently ignored. Our study aims to review our experience and outcomes of patients undergoing covered stents placement and debridement with vacuum sealing drainage (VSD).

METHODS

This study retrospectively analyzed 41 intravenous drug addicts with IFAP who received covered stent implantation and debridement with VSD from January 2015 to December 2020. The diagnosis was based on the previous history of local injection and the presence of pulsatile mass at the injection site. All cases were confirmed by CT angiography (CTA), ultrasound, or digital subtraction angiography (DSA).  Technical success, time of wound care, and clinical outcomes were evaluated.

RESULTS

Technical success was achieved in all patients. The interval from diagnosis to treatment was 26 ± 11 hours. The time of continuous drainage with VSD was 18.79 ± 6.56 days. 38 patients (92.68%) with fresh granulation tissue were sutured and discharged from the hospital. Stents in 31(91.18%) of 34 cases were patent during follow-ups. Three patients had stent occlusion caused by thrombosis, and two of them were complicated with stent infection. The two infectious stents were removed and the femoral arteries were ligated. One of them received open-surgical reconstruction with the great saphenous because of claudication. Two patients were admitted to the hospital for rebleeding caused by  drug abuse relapse.

CONCLUSIONS

Covered stents placement is convenient and rapid to control massive hemorrhage in IFAPs of intravenous drug abuse. Early debridement of infected tissue with continued VSD may shorten the time of wound care and make the incidence of stent infection relatively low. Meanwhile, the patency in a short time follow-up is acceptable. These results indicate that covered stents implantation with VSD may be a safe, effective, and feasible measure for the treatment of IFAPs.

摘要

目的

对于采用覆膜支架治疗感染性股动脉假性动脉瘤(IFAPs),清创技术很重要,但常被忽视。我们的研究旨在回顾接受覆膜支架置入和负压封闭引流(VSD)清创的患者的经验和治疗结果。

方法

本研究回顾性分析了2015年1月至2020年12月期间41例接受覆膜支架植入和VSD清创的静脉吸毒所致IFAP患者。诊断基于既往局部注射史及注射部位存在搏动性肿块。所有病例均经CT血管造影(CTA)、超声或数字减影血管造影(DSA)证实。评估技术成功率、伤口护理时间和临床结果。

结果

所有患者均取得技术成功。从诊断到治疗的间隔时间为26±11小时。VSD持续引流时间为18.79±6.56天。38例(92.68%)有新鲜肉芽组织的患者缝合后出院。34例中的31例(91.18%)支架在随访期间通畅。3例患者因血栓形成导致支架闭塞,其中2例并发支架感染。移除了2个感染性支架并结扎股动脉。其中1例因跛行接受了大隐静脉开放手术重建。2例患者因吸毒复发再次入院出血。

结论

覆膜支架置入对于控制静脉吸毒所致IFAP的大出血方便快捷。早期对感染组织进行清创并持续VSD治疗可能缩短伤口护理时间,使支架感染发生率相对较低。同时,短期随访中的通畅率是可以接受的。这些结果表明,VSD辅助下的覆膜支架植入可能是治疗IFAP的一种安全、有效且可行的措施。

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