[重印自：重度子痫前期：法国麻醉与重症医学会（SFAR）和法国妇产科医师学会（CNGOF）的临床实践指南]
[Reprint of: Severe pre-eclampsia: guidelines for clinical practice from the French Society of anesthesiology and intensive care (SFAR) and the French College of gynaecologists and obstetricians (CNGOF)].
作者信息
Bonnet M-P, Garnier M, Keita H, Compere V, Arthuis C, Raia-Barjat T, Berveiller P, Burey J, Bouvet L, Bruyère M, Castel A, Clouqueur E, Estevez M Gonzalez, Faitot V, Fischer C, Fuchs F, Lecarpentier E, Le Gouez A, Rigouzzo A, Rossignol M, Simon E, Vial F, Vivanti A J, Zieleskewicz L, Sénat M-V, Schmitz T, Sentilhes L
机构信息
Sorbonne Université, GRC 29, DMU DREAM, Department of Anaesthesiology and Intensive Care, Armand Trousseau University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Centre de Recherche épidémiologie et Statistiques Sorbonne Paris Cité (CRESS) U1153, INSERM, Obstetrical, Perinatal and Paediatric Epidemiology (EPOPé) Research Team, Université de Paris, Paris, France.
Sorbonne Université, APHP, GRC 29, DMU DREAM, Département d'Anesthesie-réanimation, CHU Tenon, Paris, France.
出版信息
Gynecol Obstet Fertil Senol. 2022 Jan;50(1):2-25. doi: 10.1016/j.gofs.2021.11.003. Epub 2021 Nov 12.
OBJECTIVE
To provide national guidelines for the management of women with severe preeclampsia.
DESIGN
A consensus committee of 26 experts was formed. A formal conflict of interest (COI) policy was developed at the onset of the process and enforced throughout. The entire guidelines process was conducted independently of any industrial funding. The authors were advised to follow the principles of the Grading of Recommendations Assessment, Development and Evaluation (GRADE®) system to guide assessment of quality of evidence. The potential drawbacks of making strong recommendations in the presence of low-quality evidence were emphasized.
METHODS
The last SFAR and CNGOF guidelines on the management of women with severe preeclampsia was published in 2009. The literature is now sufficient for an update. The aim of this expert panel guidelines is to evaluate the impact of different aspects of the management of women with severe preeclampsia on maternal and neonatal morbidities separately. The experts studied questions within 7 domains. Each question was formulated according to the PICO (Patients Intervention Comparison Outcome) model and the evidence profiles were produced. An extensive literature review and recommendations were carried out and analyzed according to the GRADE® methodology.
RESULTS
The SFAR/CNGOF experts panel provided 25 recommendations: 8 have a high level of evidence (GRADE 1±), 9 have a moderate level of evidence (GRADE 2±), and for 7 recommendations, the GRADE method could not be applied, resulting in expert opinions. No recommendation was provided for 3 questions. After one scoring round, strong agreement was reached between the experts for all the recommendations.
CONCLUSIONS
There was strong agreement among experts who made 25 recommendations to improve practices for the management of women with severe preeclampsia.
目的
提供重度子痫前期女性管理的国家指南。
设计
成立了一个由26名专家组成的共识委员会。在该过程开始时制定了正式的利益冲突（COI）政策，并在整个过程中实施。整个指南制定过程独立于任何行业资助进行。建议作者遵循推荐分级评估、制定与评价（GRADE®）系统的原则来指导证据质量评估。强调了在证据质量低的情况下提出强烈推荐的潜在弊端。
方法
关于重度子痫前期女性管理的上一版SFAR和CNGOF指南于2009年发布。现在文献资料足以进行更新。本专家小组指南的目的是分别评估重度子痫前期女性管理不同方面对孕产妇和新生儿发病率的影响。专家们研究了7个领域内的问题。每个问题均根据PICO（患者、干预措施、对照、结局）模型制定，并生成了证据概况。根据GRADE®方法进行了广泛的文献综述并提出了建议并进行分析。
结果
SFAR/CNGOF专家小组提出了25条推荐：8条有高级别证据（GRADE 1±），9条有中等级别证据（GRADE 2±），7条推荐无法应用GRADE方法，因此为专家意见。3个问题未给出推荐。经过一轮评分后，专家们对所有推荐达成了强烈共识。
结论
提出25条推荐以改进重度子痫前期女性管理实践的专家们达成了强烈共识。
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