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简单的观察性重症监护研究:学生、护士和医生对住院和 6 个月死亡率的估计。

The simple observational critical care studies: estimations by students, nurses, and physicians of in-hospital and 6-month mortality.

机构信息

Department of Critical Care, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

Crit Care. 2021 Nov 15;25(1):393. doi: 10.1186/s13054-021-03809-w.

Abstract

BACKGROUND

Prognostic assessments of the mortality of critically ill patients are frequently performed in daily clinical practice and provide prognostic guidance in treatment decisions. In contrast to several sophisticated tools, prognostic estimations made by healthcare providers are always available and accessible, are performed daily, and might have an additive value to guide clinical decision-making. The aim of this study was to evaluate the accuracy of students', nurses', and physicians' estimations and the association of their combined estimations with in-hospital mortality and 6-month follow-up.

METHODS

The Simple Observational Critical Care Studies is a prospective observational single-center study in a tertiary teaching hospital in the Netherlands. All patients acutely admitted to the intensive care unit were included. Within 3 h of admission to the intensive care unit, a medical or nursing student, a nurse, and a physician independently predicted in-hospital and 6-month mortality. Logistic regression was used to assess the associations between predictions and the actual outcome; the area under the receiver operating characteristics (AUROC) was calculated to estimate the discriminative accuracy of the students, nurses, and physicians.

RESULTS

In 827 out of 1,010 patients, in-hospital mortality rates were predicted to be 11%, 15%, and 17% by medical students, nurses, and physicians, respectively. The estimations of students, nurses, and physicians were all associated with in-hospital mortality (OR 5.8, 95% CI [3.7, 9.2], OR 4.7, 95% CI [3.0, 7.3], and OR 7.7 95% CI [4.7, 12.8], respectively). Discriminative accuracy was moderate for all students, nurses, and physicians (between 0.58 and 0.68). When more estimations were of non-survival, the odds of non-survival increased (OR 2.4 95% CI [1.9, 3.1]) per additional estimate, AUROC 0.70 (0.65, 0.76). For 6-month mortality predictions, similar results were observed.

CONCLUSIONS

Based on the initial examination, students, nurses, and physicians can only moderately predict in-hospital and 6-month mortality in critically ill patients. Combined estimations led to more accurate predictions and may serve as an example of the benefit of multidisciplinary clinical care and future research efforts.

摘要

背景

在日常临床实践中,经常对危重症患者的死亡率进行预后评估,为治疗决策提供预后指导。与一些复杂的工具相比,医疗保健提供者进行的预后估计始终可用且易于获得,每天进行,并可能具有附加价值以指导临床决策。本研究旨在评估学生、护士和医生的估计准确性,并评估他们的联合估计与院内死亡率和 6 个月随访的相关性。

方法

简单观察性危重病研究是荷兰一家三级教学医院的前瞻性观察性单中心研究。所有急性入住重症监护病房的患者均被纳入研究。患者入住重症监护病房后 3 小时内,由医学生、护士和医生分别独立预测院内和 6 个月死亡率。使用逻辑回归评估预测值与实际结果之间的相关性;计算接收者操作特征曲线(ROC)下面积(AUROC)以评估学生、护士和医生的区分准确性。

结果

在 1010 例患者中的 827 例中,医学生、护士和医生分别预测院内死亡率为 11%、15%和 17%。学生、护士和医生的估计均与院内死亡率相关(OR 5.8,95%CI [3.7, 9.2],OR 4.7,95%CI [3.0, 7.3],OR 7.7,95%CI [4.7, 12.8])。所有学生、护士和医生的区分准确性均为中等(0.58 至 0.68 之间)。当更多的预测结果是非生存时,非生存的几率会增加(OR 2.4,95%CI [1.9, 3.1]),AUROC 为 0.70(0.65,0.76)。对于 6 个月死亡率的预测,也观察到了类似的结果。

结论

根据初步检查,学生、护士和医生只能对危重症患者的院内和 6 个月死亡率进行适度预测。联合评估可提高预测的准确性,并可能成为多学科临床护理的益处和未来研究努力的一个例子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d589/8591867/afd40400683e/13054_2021_3809_Fig1_HTML.jpg

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