Institute of Health Management, Policy, and Evaluation, University of Toronto, Toronto, Canada.
Department of Medicine, Sinai Health System, Toronto, Canada.
PLoS One. 2021 Feb 25;16(2):e0247571. doi: 10.1371/journal.pone.0247571. eCollection 2021.
Optimal end-of-life care requires identifying patients that are near the end of life. The extent to which attending physicians and trainee physicians agree on the prognoses of their patients is unknown. We investigated agreement between attending and trainee physician on the surprise question: "Would you be surprised if this patient died in the next 12 months?", a question intended to assess mortality risk and unmet palliative care needs.
This was a multicentre prospective cohort study of general internal medicine patients at 7 tertiary academic hospitals in Ontario, Canada. General internal medicine attending and senior trainee physician dyads were asked the surprise question for each of the patients for whom they were responsible. Surprise question response agreement was quantified by Cohen's kappa using Bayesian multilevel modeling to account for clustering by physician dyad. Mortality was recorded at 12 months.
Surprise question responses encompassed 546 patients from 30 attending-trainee physician dyads on academic general internal medicine teams at 7 tertiary academic hospitals in Ontario, Canada. Patients had median age 75 years (IQR 60-85), 260 (48%) were female, and 138 (25%) were dependent for some or all activities of daily living. Trainee and attending physician responses agreed in 406 (75%) patients with adjusted Cohen's kappa of 0.54 (95% credible interval 0.41 to 0.66). Vital status was confirmed for 417 (76%) patients of whom 160 (38% of 417) had died. Using a response of "No" to predict 12-month mortality had positive likelihood ratios of 1.84 (95% CrI 1.55 to 2.22, trainee physicians) and 1.51 (95% CrI 1.30 to 1.72, attending physicians), and negative likelihood ratios of 0.31 (95% CrI 0.17 to 0.48, trainee physicians) and 0.25 (95% CrI 0.10 to 0.46, attending physicians).
Trainee and attending physician responses to the surprise question agreed in 54% of cases after correcting for chance agreement. Physicians had similar discriminative accuracy; both groups had better accuracy predicting which patients would survive as opposed to which patients would die. Different opinions of a patient's prognosis may contribute to confusion for patients and missed opportunities for engagement with palliative care services.
优化临终关怀需要识别接近生命终点的患者。主治医生和住院医生在评估患者预后方面的一致性程度尚不清楚。我们调查了主治医生和住院医生对“如果这名患者在接下来的 12 个月内去世,你会感到惊讶吗?”这一问题的意见是否一致,该问题旨在评估死亡风险和未满足的姑息治疗需求。
这是一项在加拿大安大略省 7 家三级学术医院的普通内科进行的多中心前瞻性队列研究。每位负责的主治医生和高级住院医生都会对每位患者询问“意外”问题。使用贝叶斯多层次模型来量化对意外问题的回答一致性,以解释医生对的聚类影响。在 12 个月时记录死亡率。
对安大略省 7 家三级学术医院的普通内科教学团队的 30 对主治医生-住院医生进行了 546 名患者的“意外”问题调查。患者的中位年龄为 75 岁(IQR 60-85),260 名(48%)为女性,138 名(25%)需要部分或全部日常生活活动的帮助。住院医生和主治医生在 406 名(75%)患者的回答中达成一致,调整后的 Cohen's kappa 值为 0.54(95%置信区间 0.41 至 0.66)。417 名(76%)患者的存活状态得到确认,其中 160 名(417 名患者中的 38%)死亡。使用“否”回答预测 12 个月死亡率的阳性似然比分别为 1.84(95% CrI 1.55 至 2.22,住院医生)和 1.51(95% CrI 1.30 至 1.72,主治医生),阴性似然比分别为 0.31(95% CrI 0.17 至 0.48,住院医生)和 0.25(95% CrI 0.10 至 0.46,主治医生)。
在纠正机会一致性后,住院医生和主治医生对“意外”问题的回答在 54%的情况下一致。医生具有相似的鉴别准确性;两组预测患者存活的准确性都高于预测患者死亡的准确性。对患者预后的不同看法可能导致患者感到困惑,并错失接受姑息治疗服务的机会。