IEEE Trans Nanobioscience. 2022 Oct;21(4):511-519. doi: 10.1109/TNB.2021.3128393. Epub 2022 Sep 26.
Currently, DNA strand displacement is often used to build neural networks or solve logical problems. While there are few studies on the use of DNA strand displacement to solve the higher order equations. In this paper, the catalysis, degradation, annihilation and adjusted reaction modules are built through DNA strand displacement. The chemical reaction networks of the corresponding higher order equations and simultaneous equations are established through these modules, and these chemical reaction networks can be used to build analog circuits to solve binary primary simultaneous equations and binary quadratic simultaneous equations. Finally, through Visual DSD software verification, this design can realize the solution of binary primary simultaneous equations and binary quadratic simultaneous equations, which provides a reference for DNA computation in the future.
目前,DNA 链置换常用于构建神经网络或解决逻辑问题。虽然使用 DNA 链置换来解决高阶方程的研究较少。本文通过 DNA 链置换构建了催化、降解、湮灭和调节反应模块。通过这些模块建立了相应的高阶方程和联立方程组的化学反应网络,并利用这些化学反应网络构建模拟电路,用于解决二元一次联立方程组和二元二次联立方程组。最后,通过 Visual DSD 软件验证,本设计可以实现二元一次联立方程组和二元二次联立方程组的求解,为未来的 DNA 计算提供了参考。