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改良Blumgart胰肠吻合术对老年患者胰十二指肠切除术后营养状况的影响。

Effect of modified Blumgart pancreaticojejunostomy on nutritional status in elderly patients after pancreaticoduodenectomy.

作者信息

Ye Rongqiang, Zhong Wu, Long Xian, Zhang Lei

机构信息

Department of Hepatobiliary and Pancreatic Surgery, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.

Department of Gastrointestinal Surgery, Ganzhou People's Hospital Ganzhou 341000, Jiangxi, China.

出版信息

Am J Transl Res. 2021 Oct 15;13(10):11643-11652. eCollection 2021.

Abstract

OBJECTIVE

To evaluate the effect of modified Blumgart pancreaticojejunostomy on the nutritional status in elderly patients after pancreaticoduodenectomy.

METHODS

Fifty-eight elderly patients who underwent pancreaticoduodenectomy in our hospital were evenly divided into the traditional group (receiving traditional Blumgart pancreaticojejunostomy) and the modified group (receiving modified Blumgart pancreaticojejunostomy).

RESULTS

In the modified group, intraoperative blood loss and 24-h VAS score were lower and time to off-bed activity and postoperative hospital stay were shorter than those in the traditional group (<0.05). The levels of d-lactic acid, diamine oxidase, and endotoxin were increased after surgery and were higher in the modified group than those in the traditional group, while the digestive symptoms and cancer pain scores at 6 months after surgery and postoperative complication rate were lower than those of the traditional group (all <0.05). The nursing satisfaction was higher in the modified group than that in the traditional group (<0.05). The nutritional status, pancreatic endocrine function and pancreatic exocrine function showed no significant differences between the two groups.

CONCLUSION

The modified Blumgart pancreaticojejunostomy can reduce the pain level, expedite postoperative rehabilitation, and improve the intestinal mucosal barrier function and quality of life of patients while not significantly affecting postoperative nutritional status and pancreatic function.

摘要

目的

评估改良Blumgart胰肠吻合术对老年患者胰十二指肠切除术后营养状况的影响。

方法

将我院58例行胰十二指肠切除术的老年患者平均分为传统组(接受传统Blumgart胰肠吻合术)和改良组(接受改良Blumgart胰肠吻合术)。

结果

改良组术中出血量、术后24小时视觉模拟评分(VAS)较低,下床活动时间和术后住院时间短于传统组(<0.05)。术后d-乳酸、二胺氧化酶和内毒素水平升高,且改良组高于传统组,而术后6个月的消化症状和癌痛评分及术后并发症发生率低于传统组(均<0.05)。改良组护理满意度高于传统组(<0.05)。两组营养状况、胰腺内分泌功能和胰腺外分泌功能无显著差异。

结论

改良Blumgart胰肠吻合术可降低疼痛程度,加快术后康复,改善患者肠黏膜屏障功能和生活质量,同时对术后营养状况和胰腺功能无显著影响。

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