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胰十二指肠切除术后改良 Blumgart 胰肠吻合术与胰胃吻合术的比较

Comparison of Modified Blumgart pancreaticojejunostomy and pancreaticogastrostomy after pancreaticoduodenectomy.

作者信息

Wang Shin-E, Chen Shih-Chin, Shyr Bor-Uei, Shyr Yi-Ming

机构信息

Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, ROC.

Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, ROC.

出版信息

HPB (Oxford). 2016 Mar;18(3):229-35. doi: 10.1016/j.hpb.2015.09.007. Epub 2015 Nov 17.

Abstract

BACKGROUND

The aim of this study was to compare perioperative outcomes after Blumgart pancreaticojejunostomy (PJ) and pancreaticogastrostomy (PG) for pancreatic-enteric reconstruction following pancreaticoduodenectomy.

METHODS

Data of patients undergoing Blumgart PJ and PG were retrieved from prospectively-collected database. Matched patients in each surgical groups were included based on the Callery risk scoring system for clinically relevant postoperative pancreatic fistula (CR-POPF) (grades B and C). Surgical parameters and risks were compared between these two groups.

RESULTS

A total of 206 patients undergoing PD were included. Blumgart PJ was associated with shorter postoperative hospital stay (median (range) 25 (10-99) vs. 27 (10-97) days, P = 0.022). There was no surgical mortality in the Blumgart PJ group, but a 4.9% perioperative mortality in the PG, P = 0.030. The CR-POPF by Blumgrt PG is significantly lower than that by PG for overall patients (7% vs. 20%, P = 0.007), especially for those in intermediate fistula risk zone (6% vs. 21%, P =0.048) and high fistula risk zone (14% vs. 47%, P=0.038).

CONCLUSIONS

Blumgart PJ is superior to PG in terms of pancreatic leakage and surgical mortality. Blumgart PJ can be recommended for pancreatic reconstruction after PD for all pancreatic remnant subtypes.

摘要

背景

本研究旨在比较胰十二指肠切除术后采用布卢姆加特胰肠吻合术(PJ)和胰胃吻合术(PG)进行胰肠重建的围手术期结果。

方法

从前瞻性收集的数据库中检索接受布卢姆加特PJ和PG手术的患者数据。根据临床相关术后胰瘘(CR-POPF)(B级和C级)的卡勒里风险评分系统纳入各手术组中匹配的患者。比较两组之间的手术参数和风险。

结果

总共纳入了206例行胰十二指肠切除术的患者。布卢姆加特PJ与术后住院时间较短相关(中位数(范围)25(10 - 99)天 vs. 27(10 - 97)天,P = 0.022)。布卢姆加特PJ组无手术死亡,但PG组围手术期死亡率为4.9%,P = 0.030。总体患者中,布卢姆加特PG的CR-POPF显著低于PG(7% vs. 20%,P = 0.007),尤其是在中等胰瘘风险区的患者中(6% vs. 21%,P = 0.048)以及高胰瘘风险区的患者中(14% vs. 47%,P = 0.038)。

结论

在胰漏和手术死亡率方面,布卢姆加特PJ优于PG。对于所有胰腺残端亚型,布卢姆加特PJ可推荐用于胰十二指肠切除术后的胰腺重建。

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