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老年择期小手术后使用简易精神状态检查表和蒙特利尔认知评估量表对术后认知功能减退的比较

Comparison of Postoperative Cognitive Decline Using the Mini-Mental State Examination and Montreal Cognitive Assessment After Minor Elective Surgery in Elderly.

作者信息

Aytaç Ismail, Güven Aytaç Betül, Demirelli Gokhan, Kayar Çalılı Duygu, Baskan Semih, Postacı Aysun, Göğüş Nermin

机构信息

Anesthesiology, Ankara City Hospital, Ankara, TUR.

Anesthesiology and Reanimation, Bafra State Hospital, Samsun, TUR.

出版信息

Cureus. 2021 Oct 9;13(10):e18631. doi: 10.7759/cureus.18631. eCollection 2021 Oct.

Abstract

Introduction and aim Postoperative cognitive dysfunction (POCD) is an important complication associated with increased morbidity, mortality, and reduced quality of life. Generally, studies have focused on major surgery so there is little evidence of the incidence of cognitive dysfunction in minor surgery. We aimed to compare the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in terms of detecting cognitive decline in elderly patients after elective inguinal herniorrhaphy procedure with general or spinal anesthesia. Material and methods This observational study was conducted from June 2014 to March 2015 at Ankara Numune Education and Research Hospital. The type of anesthesia was determined according to the anesthesiologist's preference who is blind to the study. Patients were grouped according to anesthesia received: general or spinal anesthesia. The MMSE and MoCA were evaluated presurgery and 24 hours after the operation. Results The postoperative (24th hour) MMSE scores of patients (26.23±2.77) were significantly lower than the preoperative scores (27.17±1.93) in only the general anesthesia group (p =0.003). The postoperative (24th hour) MoCA scores (22.87±3.88 for general and 23.13±4.08 for spinal anesthesia) were significantly lower than the preoperative scores (24.32±3.19 for general and 24.35±2.84 for spinal anesthesia) in both the general and spinal anesthesia groups (p =0.000 and 0.019, respectively). The incidence of postoperative cognitive dysfunction was 32.9% using the MoCA and 15.2% using the MMSE (p=0,018). Conclusion Early POCD is an important problem after elective minor surgeries, even with spinal anesthesia, in elderly patients. The MoCA is an alternative tool that can be more sensitive than the MMSE to identify cognitive decline in elderly patients undergoing minor surgeries under both general and spinal anesthesia.

摘要

引言与目的 术后认知功能障碍(POCD)是一种重要的并发症,与发病率、死亡率增加及生活质量下降相关。一般来说,研究主要集中在大手术,因此关于小手术中认知功能障碍发生率的证据很少。我们旨在比较简易精神状态检查表(MMSE)和蒙特利尔认知评估量表(MoCA)在检测择期腹股沟疝修补术采用全身麻醉或脊髓麻醉的老年患者认知功能下降方面的效果。

材料与方法 本观察性研究于2014年6月至2015年3月在安卡拉努姆内教育与研究医院进行。麻醉类型由对研究不知情的麻醉医生根据其偏好确定。患者根据接受的麻醉方式分组:全身麻醉或脊髓麻醉。在手术前和术后24小时对MMSE和MoCA进行评估。

结果 仅在全身麻醉组中,患者术后(第24小时)的MMSE评分(26.23±2.77)显著低于术前评分(27.17±1.93)(p = 0.003)。在全身麻醉组和脊髓麻醉组中,术后(第24小时)的MoCA评分(全身麻醉组为22.87±3.88,脊髓麻醉组为23.13±4.08)均显著低于术前评分(全身麻醉组为24.32±3.19,脊髓麻醉组为24.35±2.84)(分别为p = 0.000和0.019)。使用MoCA评估的术后认知功能障碍发生率为32.9%,使用MMSE评估的为15.2%(p = 0.018)。

结论 即使采用脊髓麻醉,早期POCD在老年患者的择期小手术后也是一个重要问题。MoCA是一种替代工具,在识别接受全身麻醉和脊髓麻醉的老年小手术患者的认知功能下降方面可能比MMSE更敏感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4456/8580134/1d0e25d956ca/cureus-0013-00000018631-i01.jpg

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