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骨盆肉瘤保肢手术后的髋臼周围重建。

Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas.

作者信息

Fujiwara Tomohiro, Ogura Koichi, Christ Alexander, Bartelstein Meredith, Kenan Shachar, Fabbri Nicola, Healey John

机构信息

Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.

出版信息

J Bone Oncol. 2021 Oct 18;31:100396. doi: 10.1016/j.jbo.2021.100396. eCollection 2021 Dec.

Abstract

Limb-salvage surgery for pelvic sarcomas remains one of the most challenging surgical procedures for musculoskeletal oncologists. In the past several decades, various surgical techniques have been developed for periacetabular reconstruction following pelvic tumor resection. These methods include endoprosthetic reconstruction, allograft or autograft reconstruction, arthrodesis, and hip transposition. Each of these procedures has its own advantages and disadvantages, and there is no consensus or gold standard for periacetabular reconstruction. Consequently, this review provides an overview of the clinical outcomes for each of these reconstructive options following pelvic tumor resections. Overall, high complication rates are associated with the use of massive implants/grafts, and deep infection is generally the most common cause of reconstruction failure. Functional outcomes decline with the occurrence of severe complications. Further efforts to avoid complications using innovative techniques, such as antibiotic-laden devices, computer navigation, custom cutting jigs, and reduced use of implants/grafts, are crucial to improve outcomes, especially in patients at a high risk of complications.

摘要

骨盆肉瘤的保肢手术仍然是肌肉骨骼肿瘤学家面临的最具挑战性的外科手术之一。在过去几十年中,已经开发出各种手术技术用于骨盆肿瘤切除术后的髋臼周围重建。这些方法包括人工关节置换重建、同种异体骨或自体骨重建、关节融合术和髋关节转位术。这些手术各自都有优缺点,髋臼周围重建尚无共识或金标准。因此,本综述概述了骨盆肿瘤切除术后这些重建选择各自的临床结果。总体而言,使用大型植入物/移植物会导致高并发症发生率,深部感染通常是重建失败的最常见原因。随着严重并发症的出现,功能结果会下降。采用创新技术(如含抗生素装置、计算机导航、定制切割夹具以及减少植入物/移植物的使用)进一步努力避免并发症,对于改善结果至关重要,尤其是对于并发症高风险患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7ac/8577502/98caf98d969c/gr1.jpg

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