克山病性心肌病分钟通气量-二氧化碳产量关系的决定因素。
Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy.
机构信息
Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Fisioterapia, Diamantina, MG, Brasil.
Universidade Federal dos Vales do Jequitinhonha e Mucuri, Programa de Pós-Graduação em Reabilitação e Desempenho Funcional, Diamantina, MG, Brasil.
出版信息
Rev Soc Bras Med Trop. 2021 Nov 15;54:e0047. doi: 10.1590/0037-8682-0047-2021. eCollection 2021.
INTRODUCTION
The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown.
METHODS
Seventy-eight patients with Chagas cardiomyopathy were evaluated using clinical assessment, cardiopulmonary exercise test, echocardiography, and International Physical Activity Questionnaire.
RESULTS
Age, functional class, International Physical Activity Questionnaire score, and dilated cardiomyopathy with systolic dysfunction were independent determinants of VE/VCO2 slope, and these variables explained 63% of its variance.
CONCLUSIONS
The VE/VCO2 slope was related to age, functional class, physical activity level, and dilated cardiomyopathy with systolic dysfunction in patients with Chagas cardiomyopathy.
简介
分钟通气量-二氧化碳产量关系（VE/VCO2 斜率）是恰加斯心肌病的主要预后因素之一，但其决定因素尚不清楚。
方法
对 78 例恰加斯心肌病患者进行临床评估、心肺运动试验、超声心动图和国际体力活动问卷评估。
结果
年龄、心功能分级、国际体力活动问卷评分和伴有收缩功能障碍的扩张型心肌病是 VE/VCO2 斜率的独立决定因素，这些变量解释了其 63%的变异性。
结论
在恰加斯心肌病患者中，VE/VCO2 斜率与年龄、心功能分级、体力活动水平和伴有收缩功能障碍的扩张型心肌病有关。
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