Velagapudi Manasa, Sanley Michael J, Ased Sumaya, Destache Chris, Malesker Mark A
Division of Infectious Disease, Creighton University School of Medicine, Omaha, NE, USA.
Division of Pulmonary, Critical Care and Sleep Medicine, Creighton University School of Medicine, Omaha, NE, USA.
Am J Health Syst Pharm. 2022 Mar 7;79(6):437-445. doi: 10.1093/ajhp/zxab422.
To provide an updated review of the diagnosis and pharmacotherapy of nontuberculous mycobacteria pulmonary disease (NTM-PD) and summarize guideline recommendations for an interdisciplinary treatment approach.
A systemic approach was taken in which all articles in English in MEDLINE and PubMed were reviewed. The US National Library of Medicine's DailyMed database was used to assess drug package inserts. Analysis of NTM treatment guidelines is summarized in the article with a focus on medications, dosing, interactions, and medication monitoring.
It is critical to manage patients with NTM with a multidisciplinary team approach. Treatment is prolonged and expensive, and the potential for drug toxicity, adverse effects, and drug interactions requires monitoring. Clinical pharmacists play a role in the management of NTM.
提供非结核分枝杆菌肺病（NTM-PD）诊断和药物治疗的最新综述，并总结跨学科治疗方法的指南建议。
采用了一种系统的方法，对MEDLINE和PubMed中所有英文文章进行了综述。使用美国国立医学图书馆的DailyMed数据库评估药品说明书。本文总结了NTM治疗指南的分析，重点关注药物、剂量、相互作用和药物监测。
采用多学科团队方法管理NTM患者至关重要。治疗时间长且费用高，药物毒性、不良反应和药物相互作用的可能性需要监测。临床药师在NTM的管理中发挥作用。
