Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA; Program in Neuroscience, Indiana University, Bloomington, IN 47405, USA.
Cell Rep. 2021 Nov 16;37(7):110032. doi: 10.1016/j.celrep.2021.110032.
The human brain is composed of functionally specialized systems that support cognition. Recently, we proposed an edge-centric model for detecting overlapping communities. It remains unclear how these communities and brain systems are related. Here, we address this question using data from the Midnight Scan Club and show that all brain systems are linked via at least two edge communities. We then examine the diversity of edge communities within each system, finding that heteromodal systems are more diverse than sensory systems. Next, we cluster the entire cortex to reveal it according to the regions' edge-community profiles. We find that regions in heteromodal systems are more likely to form their own clusters. Finally, we show that edge communities are personalized. Our work reveals the pervasive overlap of edge communities across the cortex and their relationship with brain systems. Our work provides pathways for future research using edge-centric brain networks.
人类大脑由支持认知的功能特化系统组成。最近，我们提出了一种基于边缘的模型来检测重叠社区。目前尚不清楚这些社区和大脑系统之间的关系。在这里，我们使用 Midnight Scan Club 的数据来解决这个问题，并表明所有的大脑系统都通过至少两个边缘社区相互连接。然后，我们检查了每个系统内边缘社区的多样性，发现感觉系统比感觉系统更加多样化。接下来，我们对整个大脑皮层进行聚类，根据边缘社区的轮廓对其进行分类。我们发现感觉系统中的区域更有可能形成自己的聚类。最后，我们表明边缘社区是个性化的。我们的工作揭示了边缘社区在大脑皮层中的普遍重叠及其与大脑系统的关系。我们的工作为未来使用基于边缘的大脑网络的研究提供了途径。
