Pareek Tanmay, R Rajkumar, R Prabhakaran, Chidambaranathan Sugumar, O L Naganath Babu
Surgical Gastroenterology, Madras Medical College, Chennai, IND.
Cureus. 2021 Oct 13;13(10):e18743. doi: 10.7759/cureus.18743. eCollection 2021 Oct.
To evaluate the role of preoperative magnetic resonance cholangiopancreatography (MRCP) in detection of common bile duct stone (CBDS) in cases of gall stone disease (GSD).
This is a retrospective study with a prospectively maintained database, carried out in 116 patients who underwent laparoscopic cholecystectomy (LC) for GSD, from October 2017 to September 2020. Preoperative MRCP was performed in all cases.
MRCP detected CBDS in 23 out of 116 patients (19.8%) including silent CBDS in seven patients (6%). In situations of normal biochemical parameters and USG abdomen, 30.4% unnoticed CBDS out of all 23 CBDS, were discovered by MRCP. The sensitivity and specificity of aspartate aminotransferase (AST) or alanine aminotransferase (ALT) [positive predictive value (PPV): 24%; negative predictive value (NPV): 81.3%], alkaline phosphatase (ALP) (PPV: 63.2%; NPV: 88.7%), serum total bilirubin (PPV: 57.1%; NPV: 88.4%) and CBD diameter (PPV: 61.5%; NPV: 85.4%) were, respectively, 26.1% and 79.6%, 52.2% and 92.5%, 52.2% and 90.3%, and 34.8% and 94.6%. Cystic duct variations found in nine patients (7.75%). There was no bile duct injury (0%) noted in post operative patients.
With normal biochemical and USG parameters, MRCP is a valuable non-invasive investigation to detect the overlooked CBDS. After recognising the cystic duct variants, it may be possible to prevent bile duct injury. Before performing a laparoscopic cholecystectomy (LC) in GSD, a routine preoperative MRCP is highly recommended.
评估术前磁共振胰胆管造影(MRCP)在胆囊结石病(GSD)患者胆总管结石(CBDS)检测中的作用。
这是一项回顾性研究,使用前瞻性维护的数据库,研究对象为2017年10月至2020年9月期间因GSD接受腹腔镜胆囊切除术(LC)的116例患者。所有病例均进行了术前MRCP检查。
116例患者中,MRCP检测出23例CBDS(19.8%),其中7例(6%)为无症状CBDS。在生化指标和腹部超声检查正常的情况下,MRCP在所有23例CBDS中发现了30.4%未被注意到的CBDS。天冬氨酸转氨酶(AST)或丙氨酸转氨酶(ALT)[阳性预测值(PPV):24%;阴性预测值(NPV):81.3%]、碱性磷酸酶(ALP)(PPV:63.2%;NPV:88.7%)、血清总胆红素(PPV:57.1%;NPV:88.4%)和胆总管直径(PPV:61.5%;NPV:85.4%)的敏感性和特异性分别为26.1%和79.6%、52.2%和92.5%、52.2%和90.3%、34.8%和94.6%。9例患者(7.75%)发现胆囊管变异。术后患者未发现胆管损伤(0%)。
在生化指标和超声检查正常的情况下,MRCP是检测被忽视的CBDS的有价值的非侵入性检查方法。识别胆囊管变异后,有可能预防胆管损伤。在GSD患者进行腹腔镜胆囊切除术(LC)之前,强烈建议常规进行术前MRCP检查。