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细胞绘图:分子细胞生物学的一站式图解

CellPAINT: Turnkey Illustration of Molecular Cell Biology.

作者信息

Gardner Adam, Autin Ludovic, Fuentes Daniel, Maritan Martina, Barad Benjamin A, Medina Michaela, Olson Arthur J, Grotjahn Danielle A, Goodsell David S

机构信息

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States.

Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ, United States.

出版信息

Front Bioinform. 2021 Mar;1. doi: 10.3389/fbinf.2021.660936. Epub 2021 Mar 29.

Abstract

CellPAINT is an interactive digital tool that allows non-expert users to create illustrations of the molecular structure of cells and viruses. We present a new release with several key enhancements, including the ability to generate custom ingredients from structure information in the Protein Data Bank, and interaction, grouping, and locking functions that streamline the creation of assemblies and illustration of large, complex scenes. An example of CellPAINT as a tool for hypothesis generation in the interpretation of cryoelectron tomograms is presented. CellPAINT is freely available at http://ccsb.scripps.edu/cellpaint.

摘要

CellPAINT是一种交互式数字工具,可让非专业用户创建细胞和病毒分子结构的插图。我们推出了一个有多项关键改进的新版本,包括能够根据蛋白质数据库中的结构信息生成自定义成分,以及具有交互、分组和锁定功能,这些功能简化了组件的创建以及大型复杂场景的绘制。文中展示了一个将CellPAINT用作解释冷冻电子断层扫描图中假设生成工具的示例。可在http://ccsb.scripps.edu/cellpaint免费获取CellPAINT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/009a/9581012/66dcd6c2472b/fbinf-01-660936-g0001.jpg

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