Department of Cardiology, Amsterdam University Medical Center, Location AMC, Meibergdreef 5, 1105 AZ Amsterdam, the Netherlands.
Veiligheidsregio Noord-Holland Noord, Hertog Aalbrechtweg 22, 1823 DL Alkmaar, the Netherlands.
Eur Heart J. 2022 Apr 14;43(15):1465-1474. doi: 10.1093/eurheartj/ehab802.
Automated external defibrillators (AEDs) are placed in public, but the majority of out-of-hospital cardiac arrests (OHCA) occur at home.
In residential areas, 785 AEDs were placed and 5735 volunteer responders were recruited. For suspected OHCA, dispatchers activated nearby volunteer responders with text messages, directing two-thirds to an AED first and one-third directly to the patient. We analysed survival (primary outcome) and neurologically favourable survival to discharge, time to first defibrillation shock, and cardiopulmonary resuscitation (CPR) before Emergency Medical Service (EMS) arrival of patients in residences found with ventricular fibrillation (VF), before and after introduction of this text-message alert system. Survival from OHCAs in residences increased from 26% to 39% {adjusted relative risk (RR) 1.5 [95% confidence interval (CI): 1.03-2.0]}. RR for neurologically favourable survival was 1.4 (95% CI: 0.99-2.0). No CPR before ambulance arrival decreased from 22% to 9% (RR: 0.5, 95% CI: 0.3-0.7). Text-message-responders with AED administered shocks to 16% of all patients in VF in residences, while defibrillation by EMS decreased from 73% to 39% in residences (P < 0.001). Defibrillation by first responders in residences increased from 22 to 40% (P < 0.001). Use of public AEDs in residences remained unchanged (6% and 5%) (P = 0.81). Time from emergency call to defibrillation decreased from median 11.7 to 9.3 min; mean difference -2.6 (95% CI: -3.5 to -1.6).
Introducing volunteer responders directed to AEDs, dispatched by text-message was associated with significantly reduced time to first defibrillation, increased bystander CPR and increased overall survival for OHCA patients in residences found with VF.
自动体外除颤器(AED)被放置在公共场所,但大多数院外心脏骤停(OHCA)发生在家庭中。
在住宅区,放置了 785 台 AED,并招募了 5735 名志愿者响应者。对于疑似 OHCA,调度员通过短信激活附近的志愿者响应者,指示三分之二的人先去 AED,三分之一的人直接去病人处。我们分析了在有室颤(VF)的住宅中发现的患者在紧急医疗服务(EMS)到达之前的存活(主要结局)和出院时神经功能良好的存活、首次除颤电击的时间,以及 EMS 到达之前的心肺复苏(CPR),在引入此短信警报系统之前和之后。住宅中 OHCA 的存活率从 26%增加到 39%(调整后的相对风险(RR)1.5 [95%置信区间(CI):1.03-2.0])。神经功能良好存活的 RR 为 1.4(95%CI:0.99-2.0)。到达救护车前无 CPR 从 22%下降到 9%(RR:0.5,95%CI:0.3-0.7)。在住宅中,有 AED 的短信响应者对 16%的所有 VF 患者进行电击,而 EMS 的除颤次数从 73%下降到 39%(P < 0.001)。住宅中第一响应者的除颤次数从 22%增加到 40%(P < 0.001)。住宅中使用公共 AED 保持不变(6%和 5%)(P = 0.81)。从紧急呼叫到除颤的时间中位数从 11.7 分钟缩短至 9.3 分钟;平均差异-2.6(95%CI:-3.5 至-1.6)。
引入由短信调度的针对 AED 的志愿者响应者与 OHCA 患者在住宅中发现 VF 时的首次除颤时间显著缩短、旁观者 CPR 增加和整体存活率增加有关。