Burn Center, Department of General Surgery, Adana City Training and Research Hospital, Turkey.
J Burn Care Res. 2022 Jul 1;43(4):926-930. doi: 10.1093/jbcr/irab222.
Burn-related infections are challenging conditions to manage and can cause several complications entailing a complicated treatment. In this study, infection in burn patients hospitalized in burn intensive care unit (ICU) of a tertiary care hospital is investigated. This retrospective study was conducted between January 1, 2018 and December 31, 2020 in burn ICU of a tertiary care hospital. Patients with an ICU stay less than 48 hours and survival less than 72 hours were not included in the study. The demographic and clinical data as well as referral status, the type of infections and the isolated microorganisms, antibiotics used for prophylaxis, outcomes, and the mortality rate are evaluated retrospectively from patient files and the hospital registries. A total of 311 patients were included in our study cohort with a mean age of 22.11 ± 20.9 years. The burned TBSA was 28.07 ± 17.1 and abbreviated burn severity index was 5.76 ± 2.3. There were 155 patients with 283 infections and the infection rate was 45.8 per 1000 patient days. The most commonly isolated microorganisms were Candida species in bloodstream and urinary tract infections, Pseudomonas aeruginosa in burn wound infections. Most of the deaths (86.7%) occurred in patients with infections. In major burns strict adherence to isolation procedures, avoiding delays in referrals, early excision, and early wound closure are important measures to reduce infections. Each burn center should develop appropriate antibiotic strategies due to their culture results and prophylaxis with broad-spectrum antibiotics should be avoided.
烧伤相关感染的治疗极具挑战性，可能会引发多种并发症，导致治疗过程复杂。本研究旨在调查某三级医院烧伤重症监护病房（ICU）烧伤患者的感染情况。这是一项回顾性研究，于 2018 年 1 月 1 日至 2020 年 12 月 31 日在该三级医院的烧伤 ICU 进行。本研究排除了 ICU 住院时间少于 48 小时和生存时间少于 72 小时的患者。从患者病历和医院登记处回顾性评估人口统计学和临床数据以及转诊情况、感染类型和分离的微生物、预防用抗生素、转归和死亡率。共纳入 311 例患者，平均年龄为 22.11 ± 20.9 岁。烧伤总面积为 28.07 ± 17.1，简略烧伤严重度指数为 5.76 ± 2.3。有 155 例患者发生 283 次感染，感染率为 45.8/1000 患者日。最常见的分离微生物为血流和尿路感染中的念珠菌属、烧伤创面感染中的铜绿假单胞菌。大多数死亡（86.7%）发生在感染患者中。在大面积烧伤中，严格遵守隔离程序、避免转诊延误、早期切除和早期闭合创面是减少感染的重要措施。由于各烧伤中心的培养结果不同，应制定适当的抗生素策略，避免广泛使用抗生素进行预防。
