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Promyelocytic blast crisis of Philadelphia-positive thrombocythemia with translocations (9;22) and (15;17).

作者信息

Laï J L, Fenaux P, Zandecki M, Savary J B, Estienne M H, Jouet J P, Bauters F, Deminatti M

机构信息

Service de Génétique, Faculté de Médecine, Hôpital Calmette, Lille, France.

出版信息

Cancer Genet Cytogenet. 1987 Dec;29(2):311-4. doi: 10.1016/0165-4608(87)90241-x.

DOI:10.1016/0165-4608(87)90241-x
PMID:3479236
Abstract

We report a promyelocytic blast crisis in a case of Ph-positive thrombocythemia with both t(9;22) and t(15;17). Our patient confirms the specificity of t(15;17) in malignant proliferation of promyelocytes and suggests its appearance as a second genetic event in the genesis of blast crisis occurring in a Ph-positive clone.

摘要

相似文献

1
Promyelocytic blast crisis of Philadelphia-positive thrombocythemia with translocations (9;22) and (15;17).
Cancer Genet Cytogenet. 1987 Dec;29(2):311-4. doi: 10.1016/0165-4608(87)90241-x.
2
Variant translocation t(15q;17q) accompanying a promyelocytic accelerated phase of Ph-positive chronic myeloid leukemia.
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Promyelocytic blast crisis of chronic myelocytic leukemia with both t(9;22) and t(15;17) in M3 cells.
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[Masked Philadelphia chromosome: diagnostic implications in a case of chronic myeloid leukemia presenting in blast crisis].
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Megakaryocytic blast crisis in a chronic myeloid leukemia patient with a rare variant of Philadelphia rearrangement t(9;22;22) and a constitutional translocation t(3;7).一名慢性髓性白血病患者发生巨核细胞母细胞危象，该患者存在罕见的费城重排变异型t(9;22;22)和一种染色体组易位t(3;7)。
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