Quitkin F, Rifkin A, Kane J, Ramos-Lorenzi J R, Klein D F
Am J Psychiatry. 1978 May;135(5):570-2. doi: 10.1176/ajp.135.5.570.
Relapse rates of the first 35 unipolar and bipolar II manic-depressive patients who entered the controlled phase of a continuing evaluation of the prophylactic value of lithium alone or in combination with imipramine were analyzed. Lithium had a prophylactic effect in unipolar patients and possibly in bipolar II patients. Imipramine did not have a prophylactic effect in either group of patients.
对最初35例进入单独使用锂盐或锂盐与丙咪嗪联合使用预防性价值持续评估对照阶段的单相和双相II型躁郁症患者的复发率进行了分析。锂盐对单相患者有预防作用,对双相II型患者可能也有预防作用。丙咪嗪对两组患者均无预防作用。