Worthy K, Colquhoun K, Escreet R, Dunlop M, Renton J P, Douglas T A
Department of Veterinary Clinical Biochemistry, University of Glasgow Veterinary School, Garscube Estate, Bearsden, U.K.
J Reprod Fertil Suppl. 1987;35:269-76.
Plasma prolactin concentrations were measured in mares using an homologous radioimmunoassay. An annual rhythm in plasma prolactin was found, with concentrations higher during the summer than during the winter. In addition to this seasonal pattern, occasional high concentrations of prolactin were seen when concentrations were otherwise basal. Blood samples taken from mares during an oestrous cycle in October-November showed that prolactin values were basal for most of the cycle, with a marked rise in prolactin shortly before the onset of oestrus. This prolactin peak was associated with an increase in the size of the largest follicle, and with a peak of PGFM in some mares, but did not appear to be related to the LH surge. In oestrous cycles in March and May-June, there was a wide variation in the baseline of prolactin secretion, in accordance with the seasonal pattern already mentioned. However, the peak of prolactin seen around oestrus in October-November was less obvious in March and May-June. Post-partum mares showed a high but irregular profile of prolactin concentrations with no clear-cut pattern in relation to the oestrous cycle.
采用同源放射免疫分析法测定母马血浆催乳素浓度。发现血浆催乳素存在年度节律，夏季浓度高于冬季。除了这种季节性模式外，在其他情况下催乳素浓度处于基础水平时，偶尔也会出现高浓度。10月至11月发情周期期间采集的母马血样显示，在大多数周期中催乳素值处于基础水平，发情开始前不久催乳素显著升高。这个催乳素峰值与最大卵泡大小的增加以及一些母马中PGFM的峰值有关，但似乎与促黄体生成素（LH）激增无关。在3月以及5月至6月的发情周期中，催乳素分泌基线存在很大差异，这与上述季节性模式一致。然而，10月至11月发情期前后出现的催乳素峰值在3月以及5月至6月时不太明显。产后母马的催乳素浓度较高但不规则，与发情周期没有明确的模式关系。
