Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco", Catania, Italy.
EuroIntervention. 2021 Nov 19;17(10):835-847. doi: 10.4244/EIJ-D-21-00158.
Transcatheter aortic valve implantation (TAVI) has revolutionised the treatment of severe, symptomatic aortic stenosis and it is now a proven and effective alternative to surgery for patients regardless of preoperative risk stratification. Nevertheless, the consequent expansion towards younger patients with longer life expectancy focuses attention on long-term considerations. In particular, although the prevalence of coronary artery disease has been shown to decrease with the lowering of estimated risk stratification, the chance of requirement of future coronary interventions after TAVI increases dramatically as a function of patients' life expectancy. To date, however, only a few studies have investigated the feasibility and reproducibility of coronary artery cannulation after TAVI. Different conditions related mainly to aortic root anatomy and specific transcatheter aortic valve (TAV) designs and deployment have been associated with impaired coronary access after TAVI. In the present review, we will examine the conditions that may make coronary access after TAVI more challenging or even impossible.
经导管主动脉瓣植入术(TAVI)已经彻底改变了严重、有症状的主动脉瓣狭窄的治疗方法,现在无论术前风险分层如何,它都是手术的一种成熟且有效的替代方法。然而,随之而来的向预期寿命更长的年轻患者扩展的趋势,使得人们更加关注长期考虑因素。特别是,虽然已经证明随着风险分层估计值的降低,冠状动脉疾病的患病率会下降,但 TAVI 后未来冠状动脉介入治疗的需求几率会随着患者预期寿命的增加而急剧增加。然而,迄今为止,只有少数研究调查了 TAVI 后进行冠状动脉插管的可行性和可重复性。不同的情况主要与主动脉根部解剖结构以及特定的经导管主动脉瓣(TAV)设计和部署有关,这些情况与 TAVI 后冠状动脉通路受损有关。在本综述中,我们将探讨可能使 TAVI 后进行冠状动脉介入治疗更具挑战性甚至不可能的情况。