Department of Neurosciences, Unviersity of Montreal, Centre Hospitalier de l'Université de Montréal.
Department of Medicine, Division of Neurology, St. Michael's Hospital, University of Toronto, Toronto, Canada.
Neurol Clin. 2022 Feb;40(1):113-131. doi: 10.1016/j.ncl.2021.08.008.
The spectrum of demyelinating diseases affecting the central nervous system is broad. Although many have a chronic course, neuroinflammatory conditions often present with acute to subacute onset symptoms requiring hospitalization when severe. This article reviews the acute phase assessment and management of these disorders, with a particular focus on multiple sclerosis, neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody disorder, and several atypical demyelinating diseases.
影响中枢神经系统的脱髓鞘疾病谱很广。虽然许多疾病呈慢性病程，但神经炎症性疾病常表现为急性至亚急性发作症状，在严重时需要住院治疗。本文回顾了这些疾病的急性期评估和管理，特别关注多发性硬化、视神经脊髓炎谱系疾病、髓鞘少突胶质细胞糖蛋白抗体疾病和几种非典型脱髓鞘疾病。
