Moore P A, Seldin E B, Donoff R B
Anesth Prog. 1987 Sep-Oct;34(5):177-80.
Suprofen as well as codeine have been shown to be effective analgesics. In this study, a 200-mg suprofen/60-mg codeine dose is scored for analgesic efficacy and safety compared to suprofen (200 mg), codeine (60 mg), and placebo. One hundred sixty-five healthy, adult patients were asked to rate degree of pain experienced over a six-hour period after medication. The combination treatment was found to offer maximum pain relief. Dentists should be aware that flank pain and renal function abnormalities have been reported in postmarketing surveillance.
舒洛芬和可待因已被证明是有效的镇痛药。在本研究中，将200毫克舒洛芬/60毫克可待因的剂量与舒洛芬（200毫克）、可待因（60毫克）和安慰剂在镇痛效果和安全性方面进行了评分。165名健康成年患者被要求对用药后6小时内经历的疼痛程度进行评分。结果发现联合治疗能提供最大程度的疼痛缓解。牙医应注意，上市后监测中报告了腰痛和肾功能异常情况。
