Junquera J, Lanzagorta G, Russek M
National School of Biological Sciences, IPN, Mexico City.
Appetite. 1987 Oct;9(2):113-8. doi: 10.1016/0195-6663(87)90040-7.
Non-injurious tail-pinching of rats induced much more milk intake than water intake, whether the fluids were offered singly or in a choice. In both the single item and choice situations i.p. injection of adrenaline in doses of 2.5 to 15 micrograms/100 g elicited a marked, dose-related inhibition of tail-pinch-induced (TPI) milk intake, but had no consistent effect on the small amount of TPI water intake. The same doses of adrenaline injected i.m. has no inhibitory effect on TPI milk intake; on the contrary, they elicited increases (although these were not statistically significant). Thus, the effects of adrenaline (probably of hepatic origin because they are produced only by i.p. injections) which inhibit feeding caused by food deprivation are also capable of inhibiting non-homeostatic feeding induced by tail-pinch in a satiated rat.
无论单独提供液体还是提供选择，对大鼠进行无伤害性的夹尾刺激所引起的乳汁摄入量都远多于水摄入量。在单项和选择两种情况下，腹腔注射剂量为2.5至15微克/100克的肾上腺素，会对夹尾刺激诱导的（TPI）乳汁摄入产生明显的、剂量相关的抑制作用，但对少量的TPI水摄入量没有一致的影响。肌肉注射相同剂量的肾上腺素对TPI乳汁摄入没有抑制作用；相反，它们会引起增加（尽管这些增加没有统计学意义）。因此，肾上腺素（可能源自肝脏，因为只有腹腔注射才会产生这些作用）抑制由食物剥夺引起的进食的作用，也能够抑制饱足大鼠中由夹尾刺激诱导的非稳态进食。
