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Multidrug resistant Elizabethkingia meningoseptica bacteremia - Experience from a level 1 trauma centre in India.多重耐药脑膜败血伊丽莎白金菌血症——来自印度一家一级创伤中心的经验
Intractable Rare Dis Res. 2018 Aug;7(3):172-176. doi: 10.5582/irdr.2018.01077.
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Elizabethkingia Meningoseptica in a Case of Biliary Tract Infection Following Liver Transplantation.肝移植术后胆道感染病例中的脑膜败血伊丽莎白菌
Am J Case Rep. 2017 Sep 21;18:1014-1019. doi: 10.12659/ajcr.905247.
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Elizabethkingia Meningoseptica Engodenous Endophthalmitis - a case report.脑膜败血伊丽莎白菌眼内炎——病例报告。
Antimicrob Resist Infect Control. 2014 Nov 26;3(1):35. doi: 10.1186/2047-2994-3-35. eCollection 2014.
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Bad design, bad practices, bad bugs: frustrations in controlling an outbreak of Elizabethkingia meningoseptica in intensive care units.糟糕的设计、不良实践、错误的 bug:在重症监护病房控制脑膜炎败血伊丽莎白菌爆发的挫折。
J Hosp Infect. 2013 Oct;85(2):134-40. doi: 10.1016/j.jhin.2013.05.012. Epub 2013 Aug 17.
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An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius.毛里求斯发生伊丽莎白菌新生儿脑膜炎疫情。
J Infect Dev Ctries. 2011 Dec 13;5(12):834-9. doi: 10.3855/jidc.1885.
6
Clinical and microbiological analysis of Elizabethkingia meningoseptica bacteremia in adult patients in Taiwan.台湾成年患者脑膜败血伊丽莎白金菌血症的临床与微生物学分析
Scand J Infect Dis. 2009;41(9):628-34. doi: 10.1080/00365540903089476.
7
Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp: report from the SENTRY Antimicrobial Surveillance Program (1997-2001).全球金黄杆菌属菌株的抗菌药敏性及流行病学:哨兵抗菌监测计划(1997 - 2001年)报告
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8
Studies on a group of previously unclassified bacteria associated with meningitis in infants.关于一组与婴儿脑膜炎相关的先前未分类细菌的研究。
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9
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.脑膜炎败血金黄杆菌(黄杆菌属)的碳青霉烯酶:blaB的分布以及模式菌株NCTC 10016中新型金属β-内酰胺酶基因blaB3的特性分析
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10
Increasing incidence of nosocomial Chryseobacterium indologenes infections in Taiwan.台湾地区医院内吲哚金黄杆菌感染发生率上升。
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肝移植术后脑膜败血伊丽莎白金杆菌菌血症1例罕见病例

A Rare Case of Elizabethkingia meningoseptica Bacteremia After Liver Transplantation.

作者信息

Hoa Le Thi Viet, Dang Hai Pham

机构信息

Intensive Care Unit, Tam Anh General Hospital, Hanoi, Vietnam.

108 Institute of Clinical Medical and Pharmaceutical Sciences, Hanoi, Vietnam.

出版信息

Am J Case Rep. 2021 Nov 20;22:e933992. doi: 10.12659/AJCR.933992.

DOI:10.12659/AJCR.933992
PMID:34799546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8614061/
Abstract

BACKGROUND Elizabethkingia meningoseptica is an emerging pathogen in hospital environments. Immunocompromised individuals have a high risk of infections caused by E. meningoseptica, especially after transplantation. E. meningoseptica is associated with prolonged hospital stays and high mortality. In addition, E. meningoseptica is commonly resistant to many antibiotics used for gram-negative bacterial infections. We introduce the first case of E. meningoseptica bacteremia in a recipient of a liver transplant in Vietnam. CASE REPORT A 55-year-old woman with end-stage liver disease due to biliary cirrhosis underwent living donor liver transplantation at the 108 Military Central Hospital. On day 3 after transplantation, the patient had an acute cellular rejection, and corticosteroid pulse therapy was used. On day 7 after transplantation, the patient had a fever and an increased white blood cell count and C-reactive protein level. Blood cultures were positive for E. meningoseptica. Intravenous levofloxacin was administered for 10 days. The patient showed an excellent treatment response to the antibiotic therapy and was discharged. CONCLUSIONS E. meningoseptica, a multidrug-resistant gram-negative bacteria, can be considered an emerging pathogen in the hospital environment, especially in patients receiving organ transplants. Early recognition helps physicians to improve patient outcomes.

摘要

背景

脑膜败血伊丽莎白金菌是医院环境中一种新出现的病原体。免疫功能低下的个体,尤其是在移植后,感染脑膜败血伊丽莎白金菌的风险很高。脑膜败血伊丽莎白金菌与住院时间延长和高死亡率相关。此外,脑膜败血伊丽莎白金菌通常对许多用于革兰氏阴性菌感染的抗生素耐药。我们介绍越南首例肝移植受者发生脑膜败血伊丽莎白金菌血症的病例。病例报告:一名55岁因胆汁性肝硬化导致终末期肝病的女性在第108军事中心医院接受了活体供肝移植。移植后第3天,患者发生急性细胞排斥反应,采用了糖皮质激素冲击治疗。移植后第7天,患者出现发热,白细胞计数和C反应蛋白水平升高。血培养显示脑膜败血伊丽莎白金菌阳性。给予静脉注射左氧氟沙星10天。患者对抗生素治疗显示出良好的治疗反应并出院。结论:脑膜败血伊丽莎白金菌是一种多重耐药革兰氏阴性菌,可被视为医院环境中的一种新出现病原体,尤其是在接受器官移植的患者中。早期识别有助于医生改善患者预后。