Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Av Gran Via 199-203, 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Barcelona, Spain.
Eur J Nutr. 2022 Apr;61(3):1143-1165. doi: 10.1007/s00394-021-02736-4. Epub 2021 Nov 20.
Dietary lignans are phytoestrogens that are mostly found in plant-based foods, especially whole grains, seeds, nuts, legumes and vegetables. An accurate assessment of lignan exposure is crucial to evaluate their potential health benefits and to establish future recommendations and dietary guidelines. This narrative review aimed to (i) summarize the pros and the cons of the current main assessment methods for lignan exposure─i.e., dietary questionnaires, food composition tables and biomarkers, (ii) describe the individual lignans more consumed from a worldwide perspective, as well as their main food sources, (iii) determine the lignans concentrations in both urine and blood, and explore their heterogeneity among countries, and finally (iv) discuss the main determinants of lignan exposure.
膳食木脂素是植物雌激素，主要存在于植物性食物中，特别是全谷物、种子、坚果、豆类和蔬菜。准确评估木脂素的摄入量对于评估其潜在的健康益处、制定未来的建议和饮食指南至关重要。本综述旨在：（i）总结当前评估木脂素摄入量的主要方法——膳食问卷、食物成分表和生物标志物的优缺点；（ii）描述从全球角度来看，人们更多摄入的个别木脂素及其主要食物来源；（iii）确定尿液和血液中的木脂素浓度，并探讨其在各国之间的异质性；最后（iv）讨论木脂素暴露的主要决定因素。
