Multiple manifestations of SARS-CoV-2 infection have been described in the literature. Among them also oral lesions were present. These lesions seem to be very important because they are seen in various clinical presentation and should be taken into consideration in the COVID-19 diagnosis.A lot of changes and oral mucosal lesions have been described as oral manifestation of COVID-19. The most frequently observed were: aphte - like erosions, virus herpes - like erosions, oral ulcers, petechie, reddisch macule, erythema, depapilation of the tongue surface, oral hyperpigmentation, presence of opportunistic Candida infections. There is no clear evidence if oral lesions in the course of COVID-19 are related to oral mucosal damage or are due to opportunistic infections or intensive COVID-19 treatment. The next observation and study are needed to describe this relationship. However the knowledge about oral manifestation of SARS-CoV- 2 infection is important. Currently in the pandemic time even in the patients without infection confirmed by the PCR method but also in those only suspected of infection, every oral mucosa lesion might be regarded as related with COVID-19.