由眼分枝杆菌引起的导管相关血流感染：一例报告。
Catheter-related bloodstream infection caused by Tsukamurella ocularis: A case report.
机构信息
Department of General Internal Medicine, National Center for Global Health and Medicine, Tokyo, Japan; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan; Department of Infection Control, Graduate School of Medicine, Osaka University, Japan.
出版信息
J Infect Chemother. 2022 Mar;28(3):434-436. doi: 10.1016/j.jiac.2021.11.003. Epub 2021 Nov 18.
Tsukamurella spp. causes mainly bacteremia and central venous catheter-related bloodstream infections. To the best of our knowledge, there is no documented evidence that Tsukamurella ocularis causes catheter-related bloodstream infections like other species of Tsukamurella. We present a novel case of T. ocularis bacteremia in a 69-year-old woman with malignant cancer, wherein the patient was successfully treated with a peripherally inserted central venous catheter. We administered combination antimicrobial therapy to the patient, which was terminated only after confirming the absence of infection. We identified T. ocularis by sequencing three housekeeping genes that could not be identified using conventional mass spectrometry and 16S rRNA gene analysis.
柄孢壳属主要引起菌血症和与中心静脉导管相关的血流感染。据我们所知，尚无文献证据表明眼柄孢壳属可引起与其他柄孢壳属物种一样的与导管相关的血流感染。我们报告了一例 69 岁患有恶性肿瘤的女性眼柄孢壳属菌血症的新病例，患者经外周置入中心静脉导管成功治疗。我们对患者进行了联合抗菌治疗，仅在确认无感染后才停止治疗。我们通过测序三个管家基因来鉴定眼柄孢壳属，而传统的质谱和 16S rRNA 基因分析无法鉴定这些基因。
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