Suppr超能文献

评估入住重症监护病房的新冠病毒感染患者的肾功能。

Assessment of renal function among covid-19 patients admitted to the intensive care unit.

机构信息

Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.

出版信息

Pak J Pharm Sci. 2021 Sep;34(5):1645-1649.

Abstract

Severe acute respiratory viral infections are frequently associated with multiple organ failure, including acute kidney damage. The present study aimed to investigate the associated influence of COVID-19 on renal function in patients admitted to the intensive care unit in Asir region, Saudi Arabia. Thirty patients infected with COVID-19 who were referred to the intensive care unit during November and October 2020 at Asir central hospital, Asir region, Saudi Arabia were recruited. The age of patients ranged between 30 and 90 years old. Renal function tests exhibited dramatic changes in the renal biomarkers in patients with COVID-19. Blood urea levels in COVID-19 patients were significantly higher than in the control group. In addition, significantly lower albumin levels with abnormally decreased total protein levels were found in COVID-19 patients. Among the different electrolytes analyzed, a significantly lower calcium level was observed in COVID-19 patients' groups than in the controls. Renal function tests for COVID-19-infected ICU patients revealed significant changes, indicating the major impact of COVID-19 on kidney function. Monitoring renal function tests may assist in the early prognosis of COVID-19 patients. It is, therefore, crucial to increase the understanding of renal function tests in COVID-19 patients who were admitted to the hospital before their condition deteriorated.

摘要

严重急性呼吸道病毒感染常伴有多器官衰竭,包括急性肾损伤。本研究旨在探讨 COVID-19 在沙特阿拉伯阿西尔地区重症监护病房住院患者肾功能方面的相关影响。在沙特阿拉伯阿西尔地区阿西尔中央医院,2020 年 11 月和 10 月期间,招募了 30 名感染 COVID-19 并被转至重症监护病房的患者。患者年龄在 30 至 90 岁之间。肾功能试验显示 COVID-19 患者的肾生物标志物发生了明显变化。COVID-19 患者的血尿素水平明显高于对照组。此外,COVID-19 患者的白蛋白水平显著降低,总蛋白水平异常降低。在分析的不同电解质中,COVID-19 患者组的钙水平明显低于对照组。对 COVID-19 感染的 ICU 患者进行肾功能检查显示出明显变化,表明 COVID-19 对肾功能有重大影响。监测肾功能检查可能有助于对 COVID-19 患者的早期预后。因此,在患者病情恶化之前,了解入住医院的 COVID-19 患者的肾功能检查至关重要。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验