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胰岛素技术应用的障碍及新解决方案

Barriers to Uptake of Insulin Technologies and Novel Solutions.

作者信息

Pauley Meghan E, Berget Cari, Messer Laurel H, Forlenza Gregory P

机构信息

Barbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

出版信息

Med Devices (Auckl). 2021 Nov 12;14:339-354. doi: 10.2147/MDER.S312858. eCollection 2021.

Abstract

Diabetes-related technology has undergone great advancement in recent years. These technological devices are more commonly utilized in the type 1 diabetes population, which requires insulin as the primary treatment modality. Available devices include insulin pumps, continuous glucose monitors, and hybrid systems referred to as automated insulin delivery systems or hybrid closed-loop systems, which combine those two devices along with software algorithms to achieve advanced therapeutic capabilities, including automatic modulation of insulin delivery based on sensor-derived glucose levels to minimize abnormal glucose trends. Use of diabetes technology is associated with significant positive health and psychosocial outcomes, yet utilization rates are generally lacking across both adult and pediatric type 1 diabetes populations in the United States and other countries. There are consistent themes in existing barriers to technology uptake reported by individuals with type 1 diabetes or parents of children with type 1 diabetes, including physical burdens associated with wearing the devices, concerns in navigating the technology and the devices' abilities to meet user expectations, high cost, inadequate resources within the healthcare team to support device use, disparities in technology access, and psychosocial barriers. It is important to understand the common barriers to uptake of not only the automated insulin delivery systems but also their component devices (insulin pumps and continuous glucose monitors) to fully support individuals in utilizing these devices and optimizing health benefits. The purpose of this article is to summarize the current automated insulin delivery devices that are available for use in management of type 1 diabetes, review common barriers to uptake of those systems and their component devices, and provide expert opinion on existing and future solutions to identified barriers.

摘要

近年来,糖尿病相关技术取得了巨大进展。这些技术设备在1型糖尿病患者群体中使用更为普遍,1型糖尿病患者需要胰岛素作为主要治疗方式。现有设备包括胰岛素泵、持续葡萄糖监测仪以及被称为自动胰岛素输送系统或混合闭环系统的混合系统,后者将这两种设备与软件算法相结合,以实现先进的治疗功能,包括根据传感器测得的血糖水平自动调节胰岛素输送,以最大程度减少异常血糖趋势。糖尿病技术的使用与显著的积极健康和社会心理结果相关,但在美国和其他国家,成人和儿童1型糖尿病患者群体的使用率普遍较低。1型糖尿病患者或1型糖尿病患儿的父母报告的现有技术应用障碍存在一些一致的主题,包括佩戴设备带来的身体负担、操作技术和设备能否满足用户期望方面的担忧、成本高昂、医疗团队中支持设备使用的资源不足、技术获取方面的差异以及社会心理障碍。了解不仅自动胰岛素输送系统,而且其组成设备(胰岛素泵和持续葡萄糖监测仪)应用的常见障碍,对于充分支持个人使用这些设备并优化健康益处非常重要。本文的目的是总结目前可用于1型糖尿病管理的自动胰岛素输送设备,回顾这些系统及其组成设备应用的常见障碍,并就已识别障碍的现有和未来解决方案提供专家意见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8abe/8594891/e4bff578a39c/MDER-14-339-g0001.jpg

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