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The metformin in tuberous sclerosis (MiTS) study: A randomised double-blind placebo-controlled trial.结节性硬化症中的二甲双胍（MiTS）研究：一项随机双盲安慰剂对照试验。
EClinicalMedicine. 2021 Jan 14;32:100715. doi: 10.1016/j.eclinm.2020.100715. eCollection 2021 Feb.
2
The journey of metformin from glycaemic control to mTOR inhibition and the suppression of tumour growth.二甲双胍从血糖控制到 mTOR 抑制和肿瘤生长抑制的历程。
Br J Clin Pharmacol. 2019 Jan;85(1):37-46. doi: 10.1111/bcp.13780. Epub 2018 Nov 8.
3
mTOR Inhibitors in Tuberous Sclerosis Complex.mTOR 抑制剂在结节性硬化症中的应用。
Curr Neuropharmacol. 2012 Dec;10(4):404-15. doi: 10.2174/157015912804143595.
4
Tuberous sclerosis complex: a review of the management of epilepsy with emphasis on surgical aspects.结节性硬化症：癫痫治疗综述，重点关注外科治疗方面
Childs Nerv Syst. 2006 Aug;22(8):896-908. doi: 10.1007/s00381-006-0130-7. Epub 2006 Jun 13.
5
Managing epilepsy in tuberous sclerosis complex.治疗结节性硬化症相关癫痫
J Child Neurol. 2004 Sep;19(9):680-6. doi: 10.1177/08830738040190090801.
6
Non-penetrance in tuberous sclerosis.结节性硬化症的外显不全
Lancet. 2000 May 13;355(9216):1698. doi: 10.1016/s0140-6736(00)02247-9.

Metformin for the management of tuberous sclerosis: What does the evidence tell us?

作者信息

Srinivasan Anirudh, Naga Shashi Kiran Beti, Koduvath Abdulla, Pal Auroprakash, Suresh Ananthu, Kannan Amudhan, Ravichandran Mirunalini

机构信息

Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

出版信息

EXCLI J. 2021 Sep 27;20:1474-1475. doi: 10.17179/excli2021-4213. eCollection 2021.

DOI:10.17179/excli2021-4213
PMID:34803555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8600156/
Abstract
摘要