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Recent updates on antidiabetic and antiobesity potential of carnosic acid.

作者信息

Nair Diya S, Niharika Digumarthy, Madhavan Aishwariya, Sharma Shweta, Joshi Apurva Kumar Ramesh

机构信息

Department of Biochemistry, School of Sciences (B1), Jain (Deemed to be University), JC Road, Bangalore, Karnataka, India 560041.

出版信息

EXCLI J. 2021 Sep 28;20:1476-1481. doi: 10.17179/excli2021-4259. eCollection 2021.

DOI:10.17179/excli2021-4259
PMID:34803556
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8600157/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1838/8600157/8a7016ec3039/EXCLI-20-1476-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1838/8600157/8a7016ec3039/EXCLI-20-1476-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1838/8600157/8a7016ec3039/EXCLI-20-1476-t-001.jpg

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Beta-agonists as antiobesity, antidiabetic and nutrient partitioning agents.β-激动剂作为抗肥胖、抗糖尿病和营养分配剂。
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Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells.迷迭香酸和鼠尾草酸通过激活 AMPK 抑制糖异生和脂质生成基因的表达并抑制 HepG2 细胞的增殖。
Int J Mol Sci. 2021 Apr 14;22(8):4040. doi: 10.3390/ijms22084040.
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Carnosic acid prevented olanzapine-induced metabolic disorders through AMPK activation.熊果酸通过激活 AMPK 预防奥氮平诱导的代谢紊乱。
Mol Biol Rep. 2020 Oct;47(10):7583-7592. doi: 10.1007/s11033-020-05825-5. Epub 2020 Sep 14.
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Refined exposure assessment of extracts of rosemary (E 392) from its use as food additive.
对迷迭香提取物(E 392)作为食品添加剂使用时的精细暴露评估。
EFSA J. 2018 Aug 2;16(8):e05373. doi: 10.2903/j.efsa.2018.5373. eCollection 2018 Aug.
4
A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD).在2型糖尿病(TSD)患者中,用迷迭香茶(迷迭香叶)替代葡萄糖进行缩短疗程的治疗。
J Popul Ther Clin Pharmacol. 2019 Dec 3;26(4):e18-e28. doi: 10.15586/jptcp.v26i4.634.
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Interaction mechanism of carnosic acid against glycosidase (α-amylase and α-glucosidase).迷迭香酸抑制糖苷酶(α-淀粉酶和α-葡萄糖苷酶)的相互作用机制。
Int J Biol Macromol. 2019 Oct 1;138:846-853. doi: 10.1016/j.ijbiomac.2019.07.179. Epub 2019 Jul 26.
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Development and Validation of an Analytical Method Based on HPLC-ELSD for the Simultaneous Determination of Rosmarinic Acid, Carnosol, Carnosic Acid, Oleanolic Acid and Ursolic Acid in Rosemary.基于 HPLC-ELSD 的同时测定迷迭香中迷迭香酸、鼠尾草酸、鼠尾草酚、齐墩果酸和熊果酸的分析方法的建立与验证。
Molecules. 2019 Jan 17;24(2):323. doi: 10.3390/molecules24020323.
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Nutrients. 2018 Dec 15;10(12):1984. doi: 10.3390/nu10121984.
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Phytomedicine. 2018 Aug 1;47:161-173. doi: 10.1016/j.phymed.2018.04.031. Epub 2018 Apr 17.
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Int J Mol Med. 2018 Jul;42(1):193-207. doi: 10.3892/ijmm.2018.3593. Epub 2018 Mar 27.
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Protective effect of rosmarinic acid and carnosic acid against streptozotocin-induced oxidation, glycation, inflammation and microbiota imbalance in diabetic rats.迷迭香酸和鼠尾草酸对链脲佐菌素诱导的糖尿病大鼠氧化、糖基化、炎症和微生物群落失衡的保护作用。
Food Funct. 2018 Feb 21;9(2):851-860. doi: 10.1039/c7fo01508a.