与乳糜泻相关的扩张型心肌病：一例报告。
Dilated cardiomyopathy associated with celiac disease: A case report.
作者信息
Elnour Salma, Hashim Maram, Ibrahim Halah
机构信息
Department of Internal Medicine Sheikh khalifa Medical City Abu Dhabi United Arab Emirates.
出版信息
Clin Case Rep. 2021 Nov 12;9(11):e04990. doi: 10.1002/ccr3.4990. eCollection 2021 Nov.
BACKGROUND
Celiac disease, an immune-mediated inflammation of the small intestine, occurs in genetically predisposed individuals, and is caused by sensitivity to dietary gluten and related proteins. The global prevalence is approximately 1%. Celiac disease is frequently associated with extra-intestinal manifestations, including iron deficiency anemia, dermatologic eruptions, type 1 diabetes mellitus, thyroid disease, and connective tissue disorders, but is rarely associated with cardiomyopathy.
CASE PRESENTATION
Our case describes a 33-year-old woman, who presented with exertional dyspnea and fatigue, and was diagnosed with severe iron deficiency anemia and dilated cardiomyopathy, secondary to celiac disease.
CONCLUSION
High clinical suspicion is needed to identify celiac disease in patients diagnosed with dilated cardiomyopathy, as an improvement in cardiac function has been reported with strict adherence to a gluten-free diet.
背景
乳糜泻是一种由免疫介导的小肠炎症，发生于具有遗传易感性的个体，由对膳食麸质及相关蛋白质敏感所致。全球患病率约为1%。乳糜泻常伴有肠外表现，包括缺铁性贫血、皮肤疹、1型糖尿病、甲状腺疾病和结缔组织病，但很少与心肌病相关。
病例报告
我们的病例描述了一名33岁女性，她因劳力性呼吸困难和疲劳就诊，被诊断为继发于乳糜泻的严重缺铁性贫血和扩张型心肌病。
结论
对于诊断为扩张型心肌病的患者，需要高度临床怀疑以识别乳糜泻，因为据报道严格坚持无麸质饮食可改善心脏功能。
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