Kourtidis Savvas, Saravakos Panagiotis, Fiehn Christoph, Preyer Serena
Otorhinolaryngology and Head and Neck Surgery, Charité Universitätsmedizin, Berlin, DEU.
Otorhinolaryngology and Head and Neck Surgery, ViDia Kliniken, Karlsruhe, DEU.
Cureus. 2021 Oct 19;13(10):e18907. doi: 10.7759/cureus.18907. eCollection 2021 Oct.
Inflammatory pseudotumor (IP) is a rare pathologic condition that easily can be confounded with malignancy. The clinical presentation depends on the site of occurrence and the radiological or laboratory findings are not specific. Diagnosis can be established only with histology. We report a case of a 64-year-old woman with IP in an uncommon localization, the parapharyngeal space extending to skull base. Although the diagnosis was not certain after histopathological examination, broad diagnostic workup helped to exclude malignancy or bacterial infection and led to diagnosis of an IP by exclusion. We observed a good clinical and radiological regression of symptoms after administration of oral immunosuppressants, confirming the immunological mechanism of the disease.
炎性假瘤（IP）是一种罕见的病理状况，很容易与恶性肿瘤相混淆。临床表现取决于发病部位，放射学或实验室检查结果并无特异性。只有通过组织学检查才能确诊。我们报告一例64岁女性患者，其炎性假瘤发生于不常见的部位——咽旁间隙并延伸至颅底。尽管组织病理学检查后诊断仍不明确，但广泛的诊断性检查有助于排除恶性肿瘤或细菌感染，并通过排除法确诊为炎性假瘤。我们观察到口服免疫抑制剂后症状在临床和放射学上有良好的消退，证实了该病的免疫机制。
