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免疫功能正常的患者使用鼻内可卡因后发生侵袭性鼻窦炎。

Invasive sinusitis in an immunocompetent patient using intranasal cocaine.

作者信息

Bougioukas Lauren, Campbell Brendan, Crooker Kyle, Freed Jason A, Wilcock Jonathan, Singh Devika, Hale Andrew J

机构信息

Larner College of Medicine, University of Vermont, Burlington, VT, United States.

University of Vermont Medical Center, Burlington, VT, United States.

出版信息

IDCases. 2021 Nov 2;26:e01327. doi: 10.1016/j.idcr.2021.e01327. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01327
PMID:34804802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8585617/
Abstract

Invasive fungal sinusitis is a rare and potentially fatal infection that tends to occur in immunocompromised hosts. Presented is the case of a 33-year-old immunocompetent male with several months of recurrent facial and nasal pain refractory to several antibacterial courses before a diagnosis of invasive sinusitis was made. The patient's symptoms and infection were successfully treated with a combination of surgical debridement and voriconazole. The authors review the epidemiology, risk factors, diagnosis, and treatment of invasive fungal sinusitis due to .

摘要

侵袭性真菌性鼻窦炎是一种罕见且可能致命的感染,往往发生在免疫功能低下的宿主中。本文介绍了一例33岁免疫功能正常的男性病例,该患者在诊断为侵袭性鼻窦炎之前,面部和鼻部反复疼痛数月,经多个抗菌疗程治疗无效。通过手术清创和伏立康唑联合治疗,患者的症状和感染得到了成功控制。作者回顾了侵袭性真菌性鼻窦炎的流行病学、危险因素、诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/8585617/a7018e2ebbb4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/8585617/a7018e2ebbb4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75de/8585617/a7018e2ebbb4/gr1.jpg

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Immunol Med. 2019 Jun;42(2):94-98. doi: 10.1080/25785826.2019.1657377. Epub 2019 Aug 30.
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Sarcoidosis of the paranasal sinuses.鼻窦结节病。
Eur Arch Otorhinolaryngol. 2019 Jul;276(7):1969-1974. doi: 10.1007/s00405-019-05388-7. Epub 2019 Mar 21.
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Slowly progressive invasive rhino-orbito-cerebral aspergillosis: case report and literature review.缓慢进展性侵袭性鼻眶脑曲霉病:病例报告及文献复习
Clin Case Rep. 2017 Jan 26;5(3):218-224. doi: 10.1002/ccr3.798. eCollection 2017 Mar.
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Invasive fungal sinusitis in the pediatric population: Systematic review with quantitative synthesis of the literature.儿童侵袭性真菌性鼻窦炎:文献的系统评价与定量综合分析
Int J Pediatr Otorhinolaryngol. 2016 Nov;90:231-235. doi: 10.1016/j.ijporl.2016.09.019. Epub 2016 Sep 17.
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Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.曲霉病诊断和管理实践指南:美国感染病学会2016年更新版
Clin Infect Dis. 2016 Aug 15;63(4):e1-e60. doi: 10.1093/cid/ciw326. Epub 2016 Jun 29.
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Yonsei Med J. 2015 Sep;56(5):1453-6. doi: 10.3349/ymj.2015.56.5.1453.
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