Aspergillosis sinusitis with cranio-orbital spread in an apparently immunocompetent patient.

Intracranial fungal infections are unusual and typically described in immunocompromised hosts. The authors describe a rare case of an immunocompetent white man presenting with blindness after Aspergillus fumigatus infection of the ethmoidal air sinus with spread to the orbital apex and the frontal lobe. This was successfully treated by surgical drainage via a frontal craniotomy and long-term antifungal therapy with voriconazole.