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前列腺脓肿患者流行病学及微生物学的变化:葡萄球菌感染增加

The Changing Epidemiology and Microbiology of Patients With Prostate Abscess: Increase in Staphylococcal Infection.

作者信息

McCormick David W, Kaplan Julika, Whigham Cliff, Coburn Michael, Greenberg Stephen B

机构信息

Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA.

Ben Taub Hospital, Houston, Texas, USA.

出版信息

Open Forum Infect Dis. 2021 Nov 17;8(11):ofab503. doi: 10.1093/ofid/ofab503. eCollection 2021 Nov.

Abstract

BACKGROUND

Prostatic abscesses are rare and have been most commonly associated with gram-negative bacteria; however, has emerged as a leading cause, particularly in persons who are immunocompromised.

METHODS

We conducted a retrospective chart review of all patients discharged from Ben Taub Hospital with a diagnosis of prostatic abscess during January 2011-January 2019. Demographic, clinical, microbiologic, and radiographic data were abstracted from the patients' charts and analyzed for comorbidities, causative organisms, clinical course, and outcomes.

RESULTS

We identified 32 patients with a prostatic abscess during the study period. was the most common causative organism (18/32, 56%). Most patients (24/32, 75%) were admitted to a general medicine service, and the median length of stay was 9 days. Twenty-one patients (66%) were treated with a combination of surgical drainage and antibiotic therapy; 11 (34%) were treated with antibiotics alone. All patients treated with antibiotics alone had full clinical recovery. Two patients (6.3%) died, both of whom had septic shock secondary to disseminated infection.

CONCLUSIONS

Prostatic abscesses are rare and can be difficult to diagnose, leading to significant morbidity and mortality. is a frequent causative organism especially in persons with diabetes mellitus or other immunocompromising conditions. Hematogenous spread of infection to the prostate appears common. Prostatic abscesses can serve as the nidus of disseminated infection.

摘要

背景

前列腺脓肿较为罕见,最常与革兰氏阴性菌相关;然而,(此处原文缺失关键信息)已成为主要病因,尤其是在免疫功能低下的人群中。

方法

我们对2011年1月至2019年1月期间从本陶布医院出院的所有诊断为前列腺脓肿的患者进行了回顾性病历审查。从患者病历中提取人口统计学、临床、微生物学和影像学数据,并分析合并症、病原体、临床病程和结局。

结果

在研究期间,我们确定了32例前列腺脓肿患者。(此处原文缺失关键信息)是最常见的病原体(18/32,56%)。大多数患者(24/32,75%)入住普通内科,中位住院时间为9天。21例患者(66%)接受了手术引流和抗生素联合治疗;11例(34%)仅接受抗生素治疗。所有仅接受抗生素治疗的患者临床完全康复。2例患者(6.3%)死亡,均因播散性(此处原文缺失关键信息)感染继发感染性休克。

结论

前列腺脓肿罕见且难以诊断,可导致严重的发病率和死亡率。(此处原文缺失关键信息)是常见的病原体,尤其是在糖尿病或其他免疫功能低下的患者中。(此处原文缺失关键信息)感染经血行播散至前列腺似乎很常见。前列腺脓肿可成为播散性(此处原文缺失关键信息)感染的病灶。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8637/8600174/304d92cba8ff/ofab503_fig1.jpg

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