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采用风险分层指数模型对老年髋部骨折患者术后谵妄的危险因素进行识别:一项回顾性研究。

Identification of risk factors for postoperative delirium in elderly patients with hip fractures by a risk stratification index model: A retrospective study.

机构信息

The Department of Anesthesiology, Peking University Shougang Hospital, Beijing, China.

The Anesthesia and Operation Center, The First Medical Center, The Medical School of Chinese PLA, Beijing, China.

出版信息

Brain Behav. 2021 Dec;11(12):e32420. doi: 10.1002/brb3.2420. Epub 2021 Nov 22.

Abstract

INTRODUCTION

Postoperative delirium is one of the most common and dangerous psychiatric complications after hip surgery. The aim of this study was to investigate the incidence of postoperative delirium in elderly patients after hip fracture surgery and to identify risk factors for such, as part of developing a risk stratification index (RSI) system to predict a patient's risk of postoperative delirium.

METHODS

Elderly patients (aged 65 years or older) with hip fractures who had received surgical treatment in our hospital between March 2018 and December 2019 were retrospectively included. Clinical data were collected, and multivariate logistic regression analysis was performed to investigate the relevant risk factors of postoperative delirium. An RSI system was developed based on factors identified in the regression analysis.

RESULTS

Of 272 patients included, 52 (19.12%) experienced postoperative delirium. Drinking history (> 3/ week), the perioperative lactic acid level (Lac > 2 mmol/L), postoperative visual analog score (VAS) > 3, American Society of Anesthesiologists (ASA) physical status > II, application of the bispectral index, and preoperative diabetes were independent risk factors of postoperative delirium. When RSI ≥ 5, the rate of postoperative delirium significantly increased (p < .05).

CONCLUSION

The RSI system developed here can safely guide postoperative outcomes of elderly patients with hip fractures, and RSI ≥ 5 may be able to predict the onset of postoperative delirium.

摘要

引言

术后谵妄是髋关节手术后最常见和最危险的精神科并发症之一。本研究旨在调查老年髋部骨折手术后患者术后谵妄的发生率,并确定其相关危险因素,旨在开发一种风险分层指数(RSI)系统来预测患者术后谵妄的风险。

方法

回顾性纳入 2018 年 3 月至 2019 年 12 月在我院接受手术治疗的老年髋部骨折患者(年龄≥65 岁)。收集临床资料,采用多因素 logistic 回归分析探讨术后谵妄的相关危险因素。基于回归分析中确定的因素,建立 RSI 系统。

结果

共纳入 272 例患者,其中 52 例(19.12%)发生术后谵妄。饮酒史(>3/周)、围手术期血乳酸水平(Lac>2mmol/L)、术后视觉模拟评分(VAS)>3、美国麻醉医师协会(ASA)身体状况>II、应用脑电双频指数以及术前糖尿病是术后谵妄的独立危险因素。当 RSI≥5 时,术后谵妄发生率显著增加(p<0.05)。

结论

本研究建立的 RSI 系统可安全指导老年髋部骨折患者的术后结局,RSI≥5 可能有助于预测术后谵妄的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c685/8671782/241bf752dd13/BRB3-11-e32420-g001.jpg

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