与长期护理机构疫情中 COVID-19 传播相关的因素。

Factors associated with transmission of COVID-19 in long-term care facility outbreaks.

机构信息

School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.

Office of the Medical Health Officer, Fraser Health, Surrey, British Columbia, Canada.

出版信息

J Hosp Infect. 2022 Jan;119:118-125. doi: 10.1016/j.jhin.2021.11.008. Epub 2021 Nov 19.

Abstract

BACKGROUND

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a disproportionate impact on residents in long-term care facilities (LTCFs).

AIM

To identify risk factors associated with outbreak severity to inform current outbreak management and future pandemic preparedness planning efforts.

METHODS

A retrospective cohort study design was used to evaluate the association between non-modifiable factors (facility building, organization level, and resident population characteristics), modifiable factors (measured through an assessment tool for infection prevention and control (IPC) and pandemic preparedness), and severity of COVID-19 outbreaks (attack rate) in LTCFs.

FINDINGS

From March 1, 2020 to January 10, 2021, a total of 145 exposures to at least one confirmed case of COVID-19 in 82 LTCFs occurred. Risk factors associated with increased outbreak severity were older facility age, a resident (vs staff) index case, and poorer assessment tool performance. Specifically, for every item not met in the assessment tool, a 22% increase in the adjusted rate ratio was observed (1.2; 95% confidence interval: 1.1-1.4) after controlling for other risk factors.

CONCLUSION

Scores from an assessment tool, older building age, and the index case being a resident were associated with severity of COVID-19 outbreaks in our jurisdiction. The findings reinforce the importance of regularly assessing IPC measures and outbreak preparedness in preventing large outbreaks. Regular, systematic assessments incorporating IPC and outbreak preparedness measures may help mitigate impacts of future outbreaks and inform future pandemic preparedness planning.

摘要

背景

严重急性呼吸系统综合征冠状病毒 2 (SARS-CoV-2)对长期护理机构(LTCF)的居民造成了不成比例的影响。

目的

确定与暴发严重程度相关的风险因素,为当前暴发管理和未来大流行防范规划工作提供信息。

方法

采用回顾性队列研究设计,评估不可改变因素(设施建筑、组织层面和居民人口特征)、可改变因素(通过感染预防和控制(IPC)和大流行防范评估工具进行测量)与 LTCF 中 COVID-19 暴发严重程度(发病率)之间的关联。

发现

2020 年 3 月 1 日至 2021 年 1 月 10 日,在 82 家长期护理机构中,共有 145 次至少有 1 例确诊 COVID-19 暴露。与暴发严重程度增加相关的风险因素包括设施较老、居民(而非工作人员)首发病例以及较差的评估工具性能。具体而言,在控制其他风险因素后,评估工具中每有 1 项未满足,调整后的率比就会增加 22%(1.2;95%置信区间:1.1-1.4)。

结论

在我们的管辖范围内,评估工具评分、较老的建筑年龄和首发病例是居民与 COVID-19 暴发严重程度相关的因素。这些发现强调了定期评估感染预防控制措施和暴发防范对于防止大规模暴发的重要性。定期、系统地评估感染预防和控制措施以及暴发防范措施可能有助于减轻未来暴发的影响,并为未来大流行防范规划提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eb3/8603873/16fc39910b3a/gr1_lrg.jpg

引用本文的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索