Opt Express. 2021 Nov 22;29(24):40643-40651. doi: 10.1364/OE.445520.
Plasmonic devices can modulate light beyond the diffraction limit and thus have unique advantages in realizing an ultracompact feature size. However, in most cases, external light coupling systems are needed, resulting in a prohibitively bulky footprint. In this paper, we propose an integrated plasmonic biosensor on a vertical cavity surface emitting laser (VCSEL) platform. The plasmonic resonant wavelength of the nanohole array was designed to match (detune) with the emission peak wavelength of the VCSEL before (after) binding the molecules, thus the refractive index that represents the concentration of the molecule could be measured by monitoring the light output intensity. It shows that high contrast with relative intensity difference of 98.8% can be achieved for molecular detection at conventional concentrations. The size of the device chip could be the same as a VCSEL chip with regular specification of hundreds of micrometers in length and width. These results suggest that the proposed integrated sensor device offers great potential in realistic applications.
等离子体器件可以调制超越衍射极限的光，因此在实现超紧凑特征尺寸方面具有独特的优势。然而，在大多数情况下，需要外部光耦合系统，这导致了过大的占地面积。在本文中，我们提出了一种基于垂直腔面发射激光器 (VCSEL) 平台的集成等离子体生物传感器。纳米孔阵列的等离子体共振波长被设计为在分子结合前后与 VCSEL 的发射峰波长匹配（失谐），从而可以通过监测光输出强度来测量代表分子浓度的折射率。结果表明，在常规浓度下进行分子检测可以实现 98.8%的高对比度相对强度差。该器件芯片的尺寸可以与具有数百微米长度和宽度的常规规格的 VCSEL 芯片相同。这些结果表明，所提出的集成传感器设备在实际应用中具有很大的潜力。
