Biomedical Engineering, Military Technical College, Kobry-Elkobba, Cairo, Egypt.
Department of Engineering Physics, McMaster University, Hamilton, ONT, Canada.
Clin Dermatol. 2021 Jul-Aug;39(4):591-604. doi: 10.1016/j.clindermatol.2021.03.006. Epub 2021 Mar 19.
Skin erythema may present owing to many causes. One of the common causes is prolonged exposure to sunrays. Other than sun exposure, skin erythema is an accompanying sign of dermatologic diseases, such as psoriasis and acne. Quantifying skin erythema in patients enables the dermatologist to assess the patient's skin health. Quantitative assessment of skin erythema has been the focus of several studies. The clinical standard for erythema evaluation is visual assessment; however, this standard has some deficiencies. For instance, visual assessment is subjective and ineffectual for precise color information exchange. To overcome these limitations, in the past three decades various methodologies have been developed in an attempt to achieve objective erythema assessments, such as diffuse reflectance spectroscopy and both optical and nonoptical systems. This review considers the studies published during the past three decades and discusses the performance, the mathematical tactics for computation, and the limited capabilities of erythema assessment techniques for cutaneous diseases. The achievements and limitations of the current techniques in erythema assessment are presented. The advantages and development trends of optical and nonoptical methods are presented to make the reader aware of the present technological advances and their potential for dermatological disease research.
皮肤红斑可能由多种原因引起。其中一个常见原因是长时间暴露在阳光下。除了阳光照射外，皮肤红斑也是一些皮肤病的伴随症状，如银屑病和痤疮。定量评估患者的皮肤红斑有助于皮肤科医生评估患者的皮肤健康。皮肤红斑的定量评估一直是多项研究的重点。红斑评估的临床标准是视觉评估，但这种标准存在一些缺陷。例如，视觉评估是主观的，对于精确的颜色信息交流效果不佳。为了克服这些局限性，在过去的三十年中，已经开发出了各种方法来尝试实现客观的红斑评估，如漫反射光谱以及光学和非光学系统。本综述考虑了过去三十年发表的研究，并讨论了红斑评估技术在皮肤病中的性能、计算的数学策略以及有限的能力。介绍了当前红斑评估技术的成就和局限性。介绍了光学和非光学方法的优点和发展趋势，使读者了解当前的技术进步及其在皮肤病研究中的潜力。
