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富血小板血浆或光功能化辅助即刻种植即刻种植的生物学和美学效果:一项随机对照试验。

Biological and esthetic outcome of immediate dental implant with the adjunct pretreatment of immediate implants with platelet-rich plasma or photofunctionalization: A randomized controlled trial.

机构信息

Department of Prosthodontics, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

J Indian Prosthodont Soc. 2021 Oct-Dec;21(4):348-355. doi: 10.4103/jips.jips_217_21.

Abstract

AIM

The purpose of the study was to assess biological and esthetic outcomes of immediate dental implant in esthetic zone with the adjunct pretreatment of immediate implants with photofunctionalization or platelet-rich plasma in comparison to standard tapered root form implant without pretreatment.

SETTINGS AND DESIGN

Patients visiting department of Prosthodontics of a tertiary care health Institution. Design of the study was randomized controlled trial.

MATERIALS AND METHODS

Ninety subjects who required replacement of maxillary anterior teeth immediately after extraction were selected and randomly divided into three groups: control group and two case groups. Two case groups were treated with immediate implants with pretreatment with Photofunctionalization (PF group) or platelet-rich plasma (PRP group). Delayed loading protocol was followed with prosthesis given after 6 months. Follow-up was performed at 2 and 4 weeks and 2, 4, 6, and 12 months (P < 0.05). Biological outcomes (mean marginal bone loss, implant stability), esthetic outcome (pink esthetic score and white esthetic score), and success and survival rate were evaluated.

STATISTICAL ANALYSIS USED

Outcomes were compared using one-way ANOVA, while intragroup changes with baseline and follow up were assesed using repeated-measures ANOVA. Statistical analyses were performed using Statistical Package for Social Sciences version 25.0 (SPSS Inc., Chicago, IL, USA). The level of significance was set at <.05.

RESULTS

Mean marginal bone loss was not significantly different in PF group and PRP group than the control group. PF group and PRP group showed significantly greater implant stability as compared to the control group. Pink and white esthetic scores were not significantly different among groups.

CONCLUSION

Pretreatment of commercial dental implants with PF or PRP exhibited a statistically significant difference in implant stability but not with other outcomes.

摘要

目的

本研究旨在评估即刻植入物在美学区的生物学和美学效果,同时比较了预处理即刻植入物与光功能化或富含血小板的血浆(PRP)和标准锥形根形式植入物无预处理的效果。

设置和设计

研究对象为三级医疗机构修复科就诊的患者。研究设计为随机对照试验。

材料和方法

选择 90 名需要在拔牙后立即替换上颌前牙的患者,并将其随机分为三组:对照组和两个病例组。两个病例组分别采用即刻植入物预处理(PF 组)或富含血小板的血浆(PRP 组)。采用延迟加载方案,6 个月后给予修复体。在 2 周、4 周和 2、4、6 和 12 个月进行随访(P<0.05)。评估生物学结果(平均边缘骨丢失、种植体稳定性)、美学结果(粉红色美学评分和白色美学评分)、成功率和存活率。

统计学分析

采用单因素方差分析比较结果,采用重复测量方差分析评估组内基线和随访的变化。统计分析采用 SPSS 25.0 版(SPSS Inc.,芝加哥,IL,USA)进行。显著性水平设定为<0.05。

结果

PF 组和 PRP 组的平均边缘骨丢失与对照组相比无显著差异。PF 组和 PRP 组的种植体稳定性明显高于对照组。组间粉红色和白色美学评分无显著差异。

结论

商用种植体预处理用 PF 或 PRP 处理在种植体稳定性方面表现出统计学上的显著差异,但在其他结果方面没有差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a70/8617446/5a40acde3080/JIPS-21-348-g001.jpg

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