Department of Prosthodontics and Implantology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
Department of Periodontics and Implantology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
J Indian Prosthodont Soc. 2021 Oct-Dec;21(4):366-374. doi: 10.4103/jips.jips_331_21.
Successful functional and esthetic rehabilitation of edentulous jaws with implants depends on the optimal timing of placement, surgical protocol, materials used, cost-effectiveness, and satisfying patient needs. Increasing demand for shorter treatment times necessitates the immediate placement protocol. However, researchers have demonstrateda higher failure rate. A-PRF (Advanced platelet-rich fibrin) has exhibited accelerated bone regeneration potential. Early implant placement with a limited healing period, along with A-PRF, can be beneficial over conventional and immediate implant placement.
This prospective randomized clinical trial aims to assess the outcome of early implant placement in sockets preserved using A-PRF at six weeks and eight weeks of post-extraction. Two groups of 10 participantseach were formed. All patients underwent atraumatic extraction and socket preservation using A-PRF.
A Partial-thickness pedicle graft was raised, and the extraction socket wasclosed. Implants wereplaced in at six and eight weeks of post-extraction in group A group B, respectively. The histomorphometric analysisassessedthe bone quality present at the timeof surgery. The insertion torque values were recorded during implant placement.
The obtained data were statistically analyzed using parametric tests, namely independent T-test for intergroup comparison.
T-test for torque values indicated a significantly higher torque value at eight weeks. The meanhistomorphometric value showeda significantly higher percentage of bone formation at eight weeks than at six weeks (P = 0.03).
Within the study's limitations, early implant placement in extraction sockets preserved with A-PRF had significantly higher insertion torque values and predictable bone at eight weeks compared to six weeks.
成功实现无牙颌患者的功能和美观修复,取决于种植体的最佳植入时机、手术方案、使用材料、成本效益以及满足患者需求等因素。由于人们对更短治疗时间的需求不断增加,因此需要采用即刻植入方案。然而,研究人员已经证明这种方案的失败率更高。富血小板纤维蛋白(A-PRF)表现出加速骨再生的潜力。与传统即刻植入相比,在有限的愈合期内早期植入并使用 A-PRF 可以带来更多益处。
本前瞻性随机临床试验旨在评估在拔牙窝中使用 A-PRF 保存 6 周和 8 周后进行早期种植体植入的结果。每组形成了 10 名参与者的两个队列。所有患者均采用微创拔牙技术和 A-PRF 进行拔牙窝保存。
掀起部分厚度蒂状皮瓣,关闭拔牙窝。在第 6 周和第 8 周时,分别在 A 组和 B 组患者中植入种植体。在手术时进行组织形态计量学分析以评估骨质量。记录植入过程中的植入扭矩值。
采用参数检验,即独立 T 检验对组间进行比较,对获得的数据进行统计分析。
扭矩值的 T 检验表明,第 8 周的扭矩值明显更高。平均组织形态计量值显示,第 8 周的骨形成百分比明显高于第 6 周(P = 0.03)。
在研究的限制范围内,与第 6 周相比,在使用 A-PRF 保存的拔牙窝中进行早期种植体植入,第 8 周的植入扭矩值更高,且具有可预测性。