Department of Periodontology, ADC (R&R), Dhaula Kuan, New Delhi, India.
Indian J Dent Res. 2021 Apr-Jun;32(2):264-267. doi: 10.4103/ijdr.IJDR_619_18.
Marginal tissue recession leads to exposure of root surfaces of teeth resulting in root sensitivity, caries, or an unsightly appearance. Its management is carried out both by eliminating contributing factors as well as using surgical techniques. Platelet-rich fibrin (PRF) is a seond-generation platelet concentrate first described by Choukroun et al. in 2001. This case report is of a Millers Class II recession in 41 regions managed using PRF with a double pedicle flap.
A 25-year-old patient presented with gingival recession height of 5 mm, measured from the cemento-enamel junction (CEJ) to gingival margin. The recession width was 3 mm at the CEJ and PD of 1 mm with respect to 41 region. There was no keratinized tissue apical to recession. However, adequate keratinized tissue was clinically present on either side of the recession defect wrt 41 region. A partial thickness double pedicle flap was raised wrt 41 region. PRF was prepared by centrifuging whole blood at 2,700 RPM for 12 min. The membrane was folded to create bulk and secured over the recession defect.
The patient was reviewed at regular intervals of 01, 06, months and 01 year postoperatively. Significant coverage of denuded root was achieved with good color match and relief from sensitivity. Results were stable one year postoperatively.
Cases that present with a deep and wide recession are challenging to address owing to the extensive loss of keratinized tissue. In such cases, double pedicle flap can be carried out to augment gingiva by utilizing keratinized tissue adjacent to the defect site. Platelet concentrates like PRF contain platelet-derived growth factors that exhibit chemotactic and mitogenic properties that promote and modulate cellular functions involved in tissue healing, regeneration, and cell proliferation. PRF is an autologous biomaterial which may be used in root coverage procedures. Long-term studies with a larger sample size are required to establish PRF as a predictable method of gingival recession coverage.
边缘组织退缩会导致牙齿的牙根表面暴露,从而导致牙根敏感、龋齿或不美观。其治疗方法既包括消除致病因素,也包括采用外科技术。富血小板纤维蛋白(PRF)是第二代血小板浓缩物,由 Choukroun 等人于 2001 年首次描述。本病例报告是一例 Miller Ⅱ类 41 区牙龈退缩,采用带双蒂瓣的 PRF 治疗。
一位 25 岁患者就诊时,牙龈退缩高度为 5mm,从牙釉质牙骨质界(CEJ)到牙龈边缘测量。CEJ 处退缩宽度为 3mm,PD 为 1mm。退缩区无角化组织,但 41 区退缩缺损两侧有足够的角化组织。在 41 区制备部分厚度双蒂瓣。通过以 2700rpm 离心全血 12 分钟制备 PRF。将膜折叠以形成块状,并固定在退缩缺陷上。
患者定期于术后 01、06 个月和 01 年复查。裸露牙根的覆盖有显著改善,敏感性得到缓解,色泽匹配良好。术后一年结果稳定。
对于角化组织广泛丧失的深而宽的退缩病例,治疗具有挑战性。在这种情况下,可以进行双蒂瓣手术,利用缺损部位附近的角化组织增加牙龈。像 PRF 这样的血小板浓缩物含有血小板衍生的生长因子,具有趋化和有丝分裂特性,可促进和调节参与组织愈合、再生和细胞增殖的细胞功能。PRF 是一种自体生物材料,可用于根覆盖手术。需要进行长期的、样本量更大的研究,以确立 PRF 作为一种可预测的牙龈退缩覆盖方法。