在无金属、无氧化剂和无外源电解质条件下芳香胺的选择性电化学硫氰化反应。

Selective electrochemical -thiocyanation of aromatic amines under metal-, oxidant- and exogenous-electrolyte-free conditions.

作者信息

Zhang Ying, Gao Huanjie, Guo Jiabao, Zhang Hao, Yao Xiaoquan

机构信息

Department of Applied Chemistry, School of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, P. R. China.

出版信息

Chem Commun (Camb). 2021 Dec 7;57(97):13166-13169. doi: 10.1039/d1cc05208j.

DOI:10.1039/d1cc05208j

PMID:34812816

Abstract

An electrochemical oxidative -CH-thiocyanation of aromatic amines has been developed to construct thiocyanato aromatic compounds under metal-, oxidant-, and exogenous-electrolyte-free conditions in an undivided cell. The transformation is compatible with a range of primary, secondary, and tertiary amines and shows good functional group tolerance. This approach provides an economical and environmentally benign way for -thiocyanation of aromatic amines.

摘要

已开发出一种用于芳香胺的电化学氧化 -CH-硫氰化反应，可在无分隔电解槽中，在无金属、无氧化剂和无外源电解质的条件下构建硫氰酸根取代的芳香族化合物。该转化反应适用于一系列伯胺、仲胺和叔胺，并且对官能团具有良好的耐受性。这种方法为芳香胺的 -硫氰化提供了一种经济且环境友好的途径。