Jiang C Y, Pan H, Yu X, Tian L, Wu H Y, Liu J Y, Chen Y F, Chen H Y, Zhu Y Y
Division of Infectious Disease Control and Prevention,Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China.
Division of Infectious Disease Control and Immunization,Shanghai Xuhui District Center for Disease Control and Prevention, Shanghai 200237, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Oct 10;42(10):1846-1849. doi: 10.3760/cma.j.cn112338-20210422-00333.
To discuss the challenges and problems of the prevention and control of emerging infectious diseases in Shanghai as a megacities. An imported case of cutaneous anthrax occurred in Shanghai on May 30, 2019. Shanghai Municipal Center for Disease Control & Prevention conducted an epidemiological investigation and treatment of the cases; after this case, the data of patients with cutaneous anthrax were collected, and an epidemiological study was conducted. Meanwhile, the wound and blood samples of the patient were collected for laboratory testing. Of the seven wound samples of the patient, 6 were positive for the nucleic acid test, and the double serological test results showed a 4-fold increase in the titer of anthrax antibodies. Shanghai CDC conducted an epidemiological investigation of the confirmed cases and observed its contacts. After treatment, the patients recovered, and no other issues appeared among the 19 contacts. Shanghai must strengthen the training of clinicians on emerging infectious diseases to achieve early detection, diagnosis, and treatment of imported infectious diseases and reduce the incidence, spread, and death of the diseases. At the same time, multi-department joint prevention and control are needed to prevent and control secondary cases.
探讨作为特大城市的上海在新发传染病防控方面面临的挑战与问题。2019年5月30日上海出现1例输入性皮肤炭疽病例。上海市疾病预防控制中心对该病例进行了流行病学调查及救治；此病例之后，收集了皮肤炭疽患者的数据并开展了流行病学研究。同时，采集了患者的伤口及血液样本进行实验室检测。患者的7份伤口样本中，6份核酸检测呈阳性，双份血清学检测结果显示炭疽抗体滴度呈4倍增长。上海疾控中心对确诊病例进行了流行病学调查并观察其密切接触者。经过治疗，患者康复，19名密切接触者未出现其他情况。上海必须加强临床医生对新发传染病的培训，以实现对输入性传染病的早发现、早诊断、早治疗，降低疾病的发病率、传播率及死亡率。同时，需要多部门联合防控以防止二代病例发生。
